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2012 Vegas Information for PSW Members

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

Last year, members gathered around a few tables and enjoyed meeting each other and listening to all our recent disasters on investing.  Phil talked about managing portfolios, and rambled here and there about how great Pharmboy was ( :) ).  No, really, the time was well spent, LVModa put on a good venue for us to eat, drink, chat, and most importantly, learn.

This year we hope to have more members show up and give their take on trading, investing, as well as just meet who is whom behind the mask. Details are noted below on who, where, and when.

Who:  PSW memebers – open to anyone who want wants to pay Savi

Where:  Las Vegas – many stayed at the Vdara, but the meetings took place at Cafe Moda LV, 3400 South Jones Blvd, Las Vegas, NV 89146

When:  November 10-12

  • Saturday Night ~7 meet for dinner (dutch payment, probably Nobu) also poker for those interested.
  • Sunday 11 am – lunch at Cafe Moda, Meeting until about 4
    • Opening Remarks – Phil
    • BBBW – Ron
    • TA & Pharma Investing – Pharmboy
    • Open Mike!
  • Monday 6 am – breakfast and be there before the market opens until market closing (about 1 pm)

Costs: $200 deposit, minimum of 25 members, maximum 50 members.  Money pays for Cafe Moda venue, internet access, lunch (Nov 11) and breakfast (Nov 12).

Pay Savi S. via Paypal.  Contact info is savi_ted at hotmail dot com





Big Pharma Review Part 2

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

Throughout the global pharmaceutical industry, 47% of respondents are ‘more optimistic’ about revenue growth for their company over the next 12 months relative to the previous 12 months.  A further 28% of respondents are ‘neutral’ about revenue growth as compared with 23% who are ‘less optimistic’ about their company’s revenue prospects (InfoGrok).  China is expected to continue to be a large part of the industry's growth, where the EU (obviously) is expected to slow down.  Overall, though, the pharma industry is still working through its patent cliff, with the final last call for a few blockbusters (The Calm Before the Storm). 

This is the second installment of the Big Pharma Review where the pipelines of GlaxoSmithKline, Novartis, Eli Lilly, Sanofi, and AstraZeneca will be updated/discussed (Part 1 is here).

GlaxoSmithKline (GSK) has been in the headlines recently for its desire to acquire Human Genome Sciences for $13/share ($2.6B).  The company has plenty of cash, and it is not like it cannot afford HGSI, as GKS has a market capitalization of $114B. The company generates revenue of $43B and has a net income of $8.6B.  GSK has also increasing its stake in Theravance (THRXarticle on THRX here), and bought a German company, Cellzome, which uses a proteomics technology to analyze the efficiency of a drug and for safety profiling research.

The company's flagship products are in respiratory (Seretide/Advair (named Beyond Advair) and Avodart).  In recent news, two experimental melanoma medicines (dabrafenib and trametinib) slowed the progress of cancer with few skin complications in an early study.   Dabrafenib works by inhibiting BRAF, a mutant gene that spurs cancer cell growth in about half of melanoma patients, while trametinib is designed to thwart a related protein called MEK, which helps tumors resist an assault on BRAF.  The drug combination had a lower incidence of rash and skin lesions than had been previously reported with Roche’s Zelboraf, according to a study of 77 patients with advanced melanoma, the most-severe form of skin cancer.

Vaccines, cardiovascular and dermatology (with its Stifel acquisition from a few years ago) will continue to drive growth.  David Redfern of JPM has a very good slide deck from its 2011 Conference on GSK's revenue and pipeline here (PDF of GSK's pipeline…
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Big Pharma – Where Are We Now?

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

In this article, please revisit an article written two years ago titled, "The Calm Before the Storm."  This article focused on the patent cliff that was looming in the pharmaceutical industry, that was later picked up by the New York Times and several other bloggers!  Subsequent articles were written about big pharma company's revenue streams, and the pros and cons of of their later stage pipelines.  Other articles have also attempted to identify smaller biotechs with the potential to reap big rewards, because these biotechs are possible acquisition candidates by the big pharma companies that need to fill their coffers with new, multi-billion dollar drugs -  the so called "blockbusters."

Forbes has an informative article that projects three different revenue scenarios in in the pharmaceutical industry. Forbes's last figure (below) shows what companies will best weather the storm by combining "total company revenues."

In the 'Storm' article, it is noted that pharma growth rates should be growing less or starting to stall into 2014 due to the patent cliffs (see Table 1).  A few examples of slow growing revenue streams are (2010 -2011): Pfizer $67.1B to $67.4B; Merck $46B to $48B, JNJ $62B to $62B, and AMGN $15.1 to $15.5.  The industry is still ripe for consolidation based upon forward earnings, and the numbers of blockbusters will be dwindling.  The industry is taking on more risk in therapy areas that are unmet medical needs, but have fewer patients to treat – thus higher prices will ensue.  Monoclonal antibodies (mAb) for cancer and other 'biologics' fit this pricey niche area.

Table 1. Patent Cliff 2010 – 2012
Company Drug Indication Sales in $B (2009) Patent Expiration
Pfizer/Eisai Aricept Alzheimer’s 1 2010
Merck Cozaar Hypertension 3.6 2010
Pfizer Lipitor Cholesterol 12.5 2011
JnJ Levaquin Antibiotic 1.5 2011
Sanofi/BMS Plavix Anticoagulant 9.3 2011
AstraZeneca Seroquel Antipsychotic 4.9 2011
Lilly Zyprexa Antipsychotic 4.9 2011
Merck Singulair Asthma 4.7


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Pharmboy in Technically Speaking

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

Excerpt from Stock World Weekly, Technically Speaking, April 22, 2012. 

Courtesy of Pharmboy

That was a nice selloff – one that we have been waiting for, and there may be more to come! This gives us an opportunity to start easing into a few more positions that are already in our virtual portfolio. The virtual portfolio had a few options that we sold and that expired worthless this month: the PLX $5 April 2012 puts, and the INFI $5 April 2012 puts. 

Protalix BioTherapeutics, Inc. (PLX, $6.78) has an FDA decision coming up, and we have several positions in it still open. I’m waiting for the decision. For those that like to gamble on risky events, the May $7.5 calls make a good risk/reward for $0.80 cents. I like selling the $10 calls for $0.25 cents, which limits the upside, but also reduces the cost to $0.55 cents for the spread. 

OPKO Health, Inc. (OPK, $4.99) is another biotech I like at current prices. Scott Brown at Sabrient has also featured OPK as an insider buying play in Stock World Weekly’s April 1 issue:

Scott sent in two long trade ideas for this week’s newsletter. First, Scott likes OPKO Health Inc. (OPK, $4.73) because of the repeated insider buying of the stock. “55 buys this year … almost daily.” Scott shared an interview with Dr. Phillip Frost, OPKO’s Chairman and CEO, on Seeking Alpha, by John Eastman. Here’s the introduction:

“‘OPKO Health Inc. Is a pharmaceutical and diagnostics company headquartered in Miami, FL that develops and commercializes novel and proprietary technologies that include molecular diagnostics tests, vaccines to diagnose, treat, and prevent neurological disorders, infectious diseases, oncology, and ophthalmologic diseases. The company works in the United States, Chile, and Mexico and is headed by Phillip Frost, M.D…’ Continue reading the interview with Dr. Frost here.

OPK’s CEO continues to accumulate shares, and the stock is trading at around $5. I think selling the September $5 call and put for $1.20 combined, coupled with the purchase of shares, has a good risk/reward profile.

As for other new trades:

Vertex Pharmaceuticals (VRTX, $36.58) was already a winner once, and I think the time is ripe to start scaling in for owning shares of this company longer term. I like selling one…
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VVUS and ARNA

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

By Pharmboy at Phil's Stock World

Excerpt from Stock World Weekly, Tightening the Screws

I expect the market to continue pulling back. But biotechs should mostly hold their ground. There are a few catalysts coming up, including with the companies Vivus and Arena. Both companies have been focusing on the obesity market. VVUS has Qnexa (a combination pill of phentermine and topiramate) and ARNA has Lorqess (a novel 5-HT2c receptor agonist).

Catalyst 1 – Vivus's stock (VVUS, $22.53) rocketed up on the PDUFA thumbs up (PDUFA = Prescription Drug User Fee Act – a group of doctors and experts meet to express their opinion about a drug). The FDA usually follows the experts’ recommendation, but not always. The FDA has yet to rule. A ruling should happen on or before April 17, 2012.

For VVUS, I like playing for a failure, as the risks to me outweigh any benefits. A very conservative GAMBLE is buying an April 2012 $20/$19 bull put spread for $0.30 or less.

Catalyst 2 – Arena (ARNA, $3.07) had a strong run from the $1.20 range, and now trades at $3.

ARNA has a PDUFA date set for June 27, 2012. If VVUS gets approval, ARNA should fair well. If VVUS is rejected, ARNA still has a chance to do well due to its drug having a different mechanism, as well as due to the patent life on its molecule.

For ARNA, I like playing a July 2012 $2.50/$3.50 bull call spread for $0.35 or less. 

Trades on these companies are all- or- none scenarios – i.e., RISKY.

 





Let’s Review: My Favorite Biotechs

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

 

Good day PSW Members!  It has been a while since the last post, but biotech plays have been active in chat, as well as in Stock World Weekly with new trades, and updating existing ones.  I must say that the biotechs and pharma are doing well in my portfolio!  This article is mainly for the many new members that have joined the PSW chat over the past few months, as many of us oldie' but goodies are in the stock plays below in some form or another.

It remains my belief that the next few years are going to be big years for biotechs.  Pharma has expiring patents, and the big players continue to scour the landscape for up and coming companies and therapies.  One we played was MITI, and that was a nice winner for a longer term hold.  At PSW, buying and selling biotechs as day trades is not the style, as we invest in companies for longer term holds, or play them into major events, then reduce our risks/exposers using options and hedging strategies.

At the end of January, Infinity Pharma (INFI) dropped like a rock and we jumped an a conservative buy write that was a bit too conservative (bought the stock and sold the April $8/7 strangle).  INFI's stock is now above where it was when it dropped, amazing but this is how we like to enter biotechs, as if we bought at $10, well, it may not have recovered…..but that is water under the bridge now.  The company has 3 development candidates described below:

  • Saridegib (also known as IPI-926) is a novel, potent, oral molecule that inhibits Smoothened, a key component of the Hedgehog pathway.  The chemical is semi-synthetic derivative of the alkaloid cyclopamine.  The hedgehog pathway was noted in the Curis article here
  • Retaspimycin hydrochloride (also known as IPI-504) is an intravenously administered, potent and selective heat shock protein 90 (Hsp90) inhibitor.  HSP90 is a chaperone to other proteins – in other words, they help in the folding or unfolding of proteins as they are being made or broken down.  Think of them as the arm in a car assembly line that aid in the production or destruction of the automobile.  In cancer, HSP90 helps stabilize proteins that are upregulated in cancer.  


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Biotech Investing for 2012

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

Finding new and exciting Biotech companies that target novel mechanisms is like trying to find a needle in a haystack.  Sure there are many companies working on cutting edge science, but investing in those companies to reap the rewards of their work is a very dangerous game.  More often than not, companies fail because the mechanism does not pan out, the compound(s) do not have pharmacokinetics (get into the body or last very long in the body), or an adverse event happens that knocks years off a development timeline.  In addition, the stock can be manipulated by market makers so investors don't know which way is up.  I approach investing in biotechs as a long term prospect.  I continue to like our current portfolio of biotech companies (join in chat for many of those plays), and we continually add/subtract shares and sell/buy options on the vacillations of the market to reduce our cost basis.  I believe our virtual biotech portfolio is well positioned with many companies that have upside potential.

I am starting to dive into the pipelines of a few companies that went IPO last year, and there is one sticks out at me, Endocyte.

Endocyte (ECYT) has six programs in various stages of clinical trials.  The company was founded in 1996, has no marketed products, but boasts a pipeline of cancer/inflammatory disease  candidates with companion diagnostics.

First, understanding what the company's drugs do is important, then diving into the pipeline will make some sense.

Folate (water soluble Vitamin B9) is needed for DNA synthesis, DNA repair, and DNA methylation as well as to act as a co-factor in biological reactions.  In essence, it helps cells grow and multiply.  Now, scientists (chemists) are good at manipulating and mimicking  biological systems, and Endocyte has drugs that incorporate folate with vinca akloids attached to them (called a 'Trojan Horse' process).   The folate-drug complex binds to the folate receptor (FR) that is over-expressed on the cell surface of many cancers and is subsequently taken into the cell (endocytosis).   Molecules as diverse as small radiodiagnostic imaging agents to large DNA plasmid formulations have successfully been delivered inside FR-positive cells and tissues.  Endocyte has one type of folate-drug delivery system for different cancer types.

Endocyte's lead drug is EC145 which targets the…
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The Skinny on the Hepatitis C Market

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

For the past few years at Phil’s Stock World, many of my articles have focused on cancer therapies or the robust (or not so robust) big pharma pipelines.  I have not delved into many specific diseases, their mechanisms, and potential treatments.  Two of the hottest areas in the industry right now are fibrosis and hepatitis C.  In the fibrosis area, large deals are being made for early stage compounds in scientifically plausible, but unproven mechanisms (Gilead’s purchase of Arresto Biosciences for $225M, Bristol-Myers buying Amira Pharmaceuticals for $325M).  Fibrosis will be a topic for another write-up.  The area where there is a flurry of activity is in the treatment of hepatitis C.  Vertex and Merck received approval for their new drugs in May 2011, Incivek and Victrelis, respectively, where Roche bought Anadys Pharmaceuticals for $230M, and Gilead is purchasing Pharmassett for $11B! 

Hepatitis C (HCV) is a viral disease that is spread by blood to blood contact, and it primarily affects the liver.  The infection is often asymptomatic, but chronic infection can lead to scarring of the liver and ultimately to liver cirrhosis.  Liver cirrhosis can lead to liver failure and/or other complications, including liver cancer or life-threatening esophageal and gastric varices.1 There is no known cure or vaccine for HCV, and an estimated 180M people are infected .  The shear number of infections makes it an attractive market for pharmaceutical companies, and thus there are many drugs being clinically tested. 

Figure 2. HCV Infections

After an HCV infection, the disease enters an acute phase and subsequently, a chronic phase.  During the acute phase, people often have flu-like symptoms, decreased appetite, fatigue,abdominal pain, jaundice, and itching.  The acute phase is considered less than 6-months.  The chronic phase (50-80% of those infected) of the disease is noted by higher liver enzymes (ALT/AST), and is often discovered when people are going through a routine checkup.  The liver is often inflamed, and cirrhosis and fibrosis could also begin to set in.  Of those that are in the chronic phase of the disease, approximately 20–50% do not respond to treatment. There is a very small chance of clearing the virus spontaneously in chronic HCV carriers (0.5% to 0.74% per year).

Figure 3. Common Genotypes

Like many viruses, hepatitis C has…
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YM Biosciences – Friend or Foe

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

YM BioSciences Inc. (AMEX: YMI) develops, markets, and commercializes hematology and cancer-related products in the drug development arena.  Below is the 1 year chart showing their ascension into the $3.7 range, then precipitous drop off to almost $1. 

On the financial side, as of September 2011, the company had about $76M in cash, and was burning about $25M/yr.  The thing that we need to be aware of is that the company has filed a preliminary short form base shelf prospectus and a registration statement on Form F-10 (July 2011) for another $125M over the next 2 years, with the Canadian securities regulatory authorities and the US Securities and Exchange commission, respectively.

Over the past few years, the company has placed stock and warrant offerings for shares in the $1.20 to $1.60 range, so there is more to come – hence my not wanting to overpay.

A bit of history, in October 2009, YM BioSciences agreed to acquire all of the issued shares and options in Cytopia by scheme of arrangement. YM would exchange 1 common share for every 11.737 Cytopia shares, which would lead to the issue of 7.2 million new YM shares. This represented a share price of $0.1659, a premium of 58% over the trading price of Cytopia shares on the ASX at that time. Following the acquisition Cytopia shareholders would own 11% of YM.  This is where CYT387 came from (see below).

On the scientific side of things, the company has many drugs in the pipeline that, if they come to fruition, could give the stock and company a  bit of up side.  First, it has one drug on the market,  nimotuzumab, which is an EGF receptor-targeting humanized IgG1 mAb, for the iv infusion treatment of cancers of epithelial origin.  Many of the cancers are still in trial, including breast, lung, prostate, esophageal, head and neck and pancreatic cancers.  The drug is co-marketed with several other companies and brings in about $1M in revenue for the company. 

The Company’s flagship product is CYT-387 (in Phase 2), a small-molecule JAK1/JAK2 tyrosine kinase inhibitor, for the potential oral treatment of myeloproliferative disorders (MPD), including myelofibrosis (MF), polycythemia vera (PV) and essential thrombocythemia (ET).  JAK stands for Janus Kinase, and is a receptor that is activated by a signal from interferon,
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Welcome to the World (Of Biotech)

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

What a show we have been having in the markets.  From 10% down one month, to 20% up the next, it is truly a spectacle to behold

 

In my small world, biotechs are a fantastic investment, but the area is saturated with complex targets (aka any kinase inhibitor – see below), unknown mechanisms of action (cough! cough! ITMN), and mismanagement (DCTH anyone?), but there are always diamonds in the rough that catch the eye of a scientist (me).  We are heavily invested in big pharma (i.e., MRK, BMY, GSK) for their dividend yields and pipelines, and we have our speculative plays for growth (CRIS, SGEN, IMGN, PLX, DEPO, MITI, YMI, etc).  At this point I think it is prudent to trim some winners and losers, so that we can focus on a few more that may warrant our attention in the coming year.

I have begun to reduce OPK (winner) and DCTH (loser).  The paired loss is a bit more than I would like, as DCTH has not shown us any love due to mismanagement and setbacks.  I find the technology very sound, but the way things have been handled, I would rather move to something that may have more upside, keeping 1/2 of my position in DCTH to recover any future upside.  OPK is supported by the CEO (he owns a lot of stock), but there is nothing in the immediate future that excites me at this time, so why not take some off the table and let the rest run to see how/where the stock goes. 

Immunogen (IMGN) is on a tear, and we have been in and out of them since ~$5.   SGEN is the comparator here for stock price, and Seattle Genetics (SGEN) trades at a premium due to: 1. no partner (takeout candidate?), and 2. their drug is approved.   That is where I believe IMGN can go….time will tell.  I am adding to IMGN slowly, selling calls and puts along the way.

Ariad (ARIA) is also on a roll.  The company has the best in class mTOR inhibitor (Ridaforolimus for bone sarcomas), and MRK has taken over all clinical development.  ARIA have a few new drugs in the pipeline, and they have a Phase 3 candidate unlicensed (Ponatinib), and this one is another drug that could…
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All About Trends

Mid-Day Update

Reminder: David is available to chat with Members, comments are found below each post.

Click here for the full report.




To learn more, sign up for David's free newsletter and receive the free report from All About Trends - "How To Outperform 90% Of Wall Street With Just $500 A Week." Tell David PSW sent you. - Ilene...

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Zero Hedge

Who Said It? "If You Take Out Saddam, I Guarantee It Will Have Enormous Positive Reverberations"

Courtesy of ZeroHedge. View original post here.

Submitted by Tyler Durden.

Submitted by Mike Krieger via Liberty Blitzkrieg blog,

In 2002, Benjamin Netanyahu already harbored some extremely strong convictions on how to deal with both Iran and Iraq. Back then, his opinions on how to handle the particular challenges each presented were quite divergent. On the one hand, he suggested beaming “reruns of Melrose Place” into Tehran, as a way of inspiring a popular uprising. In contrast, he suggested such an approach could never wor...



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Market Shadows

Kimble Charts: Utilities

Kimble Charts: Utilities

By Ilene

Chris Kimble shared his chart of the Utilities Select Sector SPDR ETF, XLU, with us.

The one month performance inset shows XLU’s uninspiring performance compared to every other ETF on the list. However, the rather steep bullish falling wedge pattern says that it may be time for a bounce.

[Click on chart to enlarge]

Chris likes XLU for a short-term bounce off the 200 day moving average at $44. One way to play this setup is to buy the XLU outright. Chris suggests a 3% stop loss on the shares.

Another bullish play is to use options in a strategy designed by Phil:

1. Buy the XL...



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Chart School

New Jobless Claims at 320K, Much Higher Than Forecast

Courtesy of Doug Short.

Here is the opening statement from the Department of Labor:

In the week ending February 28, the advance figure for seasonally adjusted initial claims was 320,000, an increase of 7,000 from the previous week's unrevised level of 313,000. The 4-week moving average was 304,750, an increase of 10,250 from the previous week's unrevised average of 294,500.

There were no special factors impacting this week's initial claims. [See full report]

Today's seasonally adjusted 320K came in well above the Investing.com forecast of 295K. The four-week moving average at 304,750 is now 25,750 above its 14-year interim low set in early November of last year.

Here is a close look at the data over the pas...



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Insider Scoop

Analysts On Dicks Sporting Goods: 'Pain Mostly Behind Us'

Courtesy of Benzinga.

Related DKS Benzinga's Top Downgrades Needham Downgrades Dick's Sporting Goods To Hold DICK's Sporting Q4 Earnings Beat on Growth Strategies - Analyst Blog (Zacks)

Dicks Sporting Goods Inc (NYSE: DKS) faces pressure from winter weather and a West Coast port slowdown, but troubles from its golf...



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Phil's Favorites

Ukraine Bans Gold Transactions Over $125, Currency Derivatives and Interbank Purchases Exceeding $10,000; Update on Black Market Rates in Ukraine

Courtesy of Mish.

Today the National Bank of Ukraine announced new capital controls on currency transactions. All Interbank Transactions Over $10,000 are Banned.
The national Bank of Ukraine has expanded the list of administrative restrictions for stabilization of the hryvnia, in particular, completely prohibiting the withdrawal of foreign dividends and limiting the purchase of foreign currency on the domestic markets.

Resolution No. 160 is effective from March 4, 2015 and is valid until June 3, 2015.

Previously, prohibitions did not target dividends on securities that are traded on stock exchanges.

The NBU has also introduced limits on the balance of banks' operations on the interbank ...



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Sabrient

Sector Detector: Stocks break out again but may be running on fumes

Courtesy of Sabrient Systems and Gradient Analytics

Despite low trading volume, a strong dollar, mixed economic and earnings reports, paralyzing weather conditions throughout much of the U.S., and ominous global news events, stocks continue to march ever higher. The world remains on edge about potential Black Swan events from the likes of Russia, Greece, or ISIS (or lone wolf extremists). Moreover, the economic recovery of the U.S. may be feeling the pull of the proverbial ball-and-chain from the rest of the world’s economies. Nevertheless, awash in investable cash, global investors see few choices better than U.S. equities.

In this weekly update, I give my view of the current market environment, offer a technical analysis of the S&P 500 chart, review our weekly fundamentals-based SectorCast rankings of the ten U.S. business sectors, and then ...



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OpTrader

Swing trading portfolio - week of March 2nd, 2015

Reminder: OpTrader is available to chat with Members, comments are found below each post.

 

This post is for all our live virtual trade ideas and daily comments. Please click on "comments" below to follow our live discussion. All of our current  trades are listed in the spreadsheet below, with entry price (1/2 in and All in), and exit prices (1/3 out, 2/3 out, and All out).

We also indicate our stop, which is most of the time the "5 day moving average". All trades, unless indicated, are front-month ATM options. 

Please feel free to participate in the discussion and ask any questions you might have about this virtual portfolio, by clicking on the "comments" link right below.

To learn more about the swing trading virtual portfolio (strategy, performance, FAQ, etc.), please click here ...



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Digital Currencies

MyCoin Exchange Disappears with Up To $387 Million, Reports Claim

Follow up from yesterday's Just the latest Bitcoin scam.

Hong Kong's MyCoin Disappears With Up To $387 Million, Reports Claim By  

Reports are emerging from Hong Kong that local bitcoin exchange MyCoin has shut its doors, taking with it possibly as much as HK$3bn ($386.9m) in investor funds.

If true, the supposed losses are a staggering amount, although this estimate is based on the company's own earlier claims that it served 3,000 clients who had invested HK$1m ($129,000) each.

...



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Pharmboy

2015 - Biotech Fever

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

PSW Members - well, what a year for biotechs!   The Biotech Index (IBB) is up a whopping 40%, beating the S&P hands down!  The healthcare sector has had a number of high flying IPOs, and beat the Tech Sector in total nubmer of IPOs in the past 12 months.  What could go wrong?

Phil has given his Secret Santa Inflation Hedges for 2015, and since I have been trying to keep my head above water between work, PSW, and baseball with my boys...it is time that something is put together for PSW on biotechs in 2015.

Cancer and fibrosis remain two of the hottest areas for VC backed biotechs to invest their monies.  A number of companies have gone IPO which have drugs/technologies that fight cancer, includin...



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Stock World Weekly

Stock World Weekly

Newsletter writers are available to chat with Members regarding topics presented in SWW, comments are found below each post.

Here's this week's Stock World Weekly.

Click here and sign in with your user name and password. 

 

...

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Option Review

SPX Call Spread Eyes Fresh Record Highs By Year End

Stocks got off to a rocky start on the first trading day in December, with the S&P 500 Index slipping just below 2050 on Monday. Based on one large bullish SPX options trade executed on Wednesday, however, such price action is not likely to break the trend of strong gains observed in the benchmark index since mid-October. It looks like one options market participant purchased 25,000 of the 31Dec’14 2105/2115 call spreads at a net premium of $2.70 each. The trade cost $6.75mm to put on, and represents the maximum potential loss on the position should the 2105 calls expire worthless at the end of December. The call spread could reap profits of as much as $7.30 per spread, or $18.25mm, in the event that the SPX ends the year above 2115. The index would need to rally 2.0% over the current level...



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Help One Of Our Own PSW Members

"Hello PSW Members –

This is a non-trading topic, but I wanted to post it during trading hours so as many eyes can see it as possible.  Feel free to contact me directly at jennifersurovy@yahoo.com with any questions.

Last fall there was some discussion on the PSW board regarding setting up a YouCaring donation page for a PSW member, Shadowfax. Since then, we have been looking into ways to help get him additional medical services and to pay down his medical debts.  After following those leads, we are ready to move ahead with the YouCaring site. (Link is posted below.)  Any help you can give will be greatly appreciated; not only to help aid in his medical bill debt, but to also show what a great community this group is.

http://www.youcaring.com/medical-fundraiser/help-get-shadowfax-out-from-the-darkness-of-medical-bills-/126743

Thank you for you time!




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About Phil:

Philip R. Davis is a founder Phil's Stock World, a stock and options trading site that teaches the art of options trading to newcomers and devises advanced strategies for expert traders...

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About Ilene:

Ilene is editor and affiliate program coordinator for PSW. She manages the site market shadows, archives, more. Contact Ilene to learn about our affiliate and content sharing programs.

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