Archive for the ‘Topic’ Category

A new vaccine is promising to advance the frontier of eliminating malaria

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A new vaccine is promising to advance the frontier of eliminating malaria

Courtesy of Simon KariukiKenya Medical Research Institute

File 20170630 8190 11ktn0z

A malaria vaccine will be piloted in Ghana, Kenya and Malawi to assess its suitability. Siegfried Modola/Reuters.

More than 30 malaria vaccine candidates are at various stages of development. The RTS,S vaccine is at the most advanced stage.

The World Health Organisation has recommended the introduction of the vaccine in Ghana, Kenya and Malawi as a pilot programme to assess its suitability in expanded immunisation programmes.

The vaccine could prove to be a powerful tool in sustaining the gains made in the last decade in reducing malaria related cases and deaths. Between 2000 and 2015, new malaria cases fell by 37% globally, and by 42% in Africa. This has been achieved through key interventions such as using treated bed nets, spraying houses with insecticides and effective antimalarial drugs.

Combined with existing malaria interventions, the vaccine would have the potential to save tens of thousands of lives in Africa. It’s important for two other reasons too.

Firstly, it would reduce the cost of managing malaria. Historically, vaccines are more cost-effective in preventing the spread of diseases compared to other methods.

Secondly, the vaccine could deal with resistance to both drugs and insecticides that’s on the rise.

The vaccine’s history

The RTS,S malaria vaccine was created in 1987 by scientists working at GlaxoSmithKline laboratories. Early clinical development of the vaccine was conducted in collaboration with the Walter Reed Army Institute for Research.

In January 2001, GlaxoSmithKline and PATH’s Malaria Vaccine Initiative entered into a public-private partnership to develop RTS,S for infants and young children living in malaria-endemic regions of sub-Saharan Africa.

Phase I and II clinical trials allowed an initial assessment of the safety and efficacy of the vaccine, initially in adult volunteers in the US and Belgium.

This was followed by adults, adolescents, children, and then infants living in malaria-endemic…
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Eight States Including Illinois Have Not Recovered Jobs Lost in Prior Recessions

Courtesy of Mish.

Illinois, Alabama, Connecticut, Michigan, Mississippi, New Mexico, Ohio, and Wyoming are the only states that still have not regained employment lost during the Great Recession or prior recessions.

The Wall Street Journal comments These Eight States Still Haven’t Regained All Their Lost Jobs.

Nonfarm payrolls in June still lag high-water marks set in 2008 or earlier in eight states struggling against headwinds like population loss and the manufacturing sector’s long-term decline: AlabamaConnecticutIllinoisMichiganMississippiNew MexicoOhio and Wyoming.

At the same time, unemployment rates were at all-time lows in six states, a mix of regions that are experiencing strong growth and other places with slower job gains and possible worker outflowsArkansasCaliforniaColoradoNorth DakotaTennessee, and Washington. Records for state unemployment rates go back to 1976.

Some areas face structural challenges, such as factory employment’s long decline. Across a swath of the industrial Midwest – Illinois, Michigan and Ohio – employment peaked back in 2000 and still hasn’t recovered to that level after two national recessions and two recoveries.

For other states, the local jobs recovery has simply been much slower than the national average.

Mike “Mish” Shedlock


Original article here.





Appeals court upholds net neutrality rules — why you should care

 

Appeals court upholds net neutrality rules — why you should care

Courtesy of Amanda LotzUniversity of Michigan

Image 20160615 14060 1hsl83g

The court ruling will keep all internet traffic treated equally. Laptop with arrows via shutterstock.com

If you like binge-watching Netflix, streaming audio or online gaming, then you should be celebrating this week. And if your business depends on reaching a wide audience online, you should join in. A federal appeals court decision this week means your internet service provider can’t slow down your access to particular sites, nor let others pay to be in a faster lane of service. It all comes down to the principle called net neutrality.

The court upheld the Obama administration’s net neutrality rules governing companies that deliver internet service to U.S. homes and businesses. At the heart of the case was the Federal Communications Commission’s February 2015 Open Internet Order. It requires that everyone – whether they are individuals, small businesses or large corporations – must have equal access to the whole internet, just like everyone has equal access to the telephone network.

Companies that provide internet service have fought against these rules. In addition to charging people for internet access at home, they hoped to earn even more money by charging content providers for priority “fast lanes” for their traffic. For example, without net neutrality rules, Comcast would be allowed to slow down (or even block) its customers’ traffic coming from Netflix – even though the Netflix viewers had already paid Comcast for internet access. And Comcast could speed things up again if Netflix directly paid Comcast even more money.

The rules were created out of concern internet service providers would reserve high-speed internet lanes for content providers who could pay for it, while relegating to slower speeds those that didn’t – or couldn’t, such as libraries, local governments and universities. Net neutrality is also important for innovation, because it protects small and start-up companies’ access to the massive online marketplace of internet users. This week’s D.C. Circuit Court of Appeals ruling establishes a level playing field for online information providers.


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Can Trump use the presidential pardon to thwart the Russia investigations?

 

Can Trump use the presidential pardon to thwart the Russia investigations?

Courtesy of Austin Sarat, Amherst College

Speculation is mounting that President Donald Trump could issue a pardon to members of his family and close associates who are suspected of colluding with Russia in the 2016 campaign.

Sen. Mark Warner, the top Democrat on the Senate Intelligence Committee, recently cautioned about “the possibility of presidential pardons in this process.”

The June 2016 meeting of Donald Trump Jr., Paul Manafort, Jared Kushner and Russian go-betweens promising dirt about Hillary Clinton raises the specter of criminal liability under campaign finance laws. Those laws prohibit foreign nationals from “directly or indirectly” making “a contribution or a donation of money or other thing of value … in connection with any Federal, State, or local election.” Damaging information on an opponent could certainly be considered a “thing of value” during a campaign.

Not everyone agrees that Trump’s son, son-in-law and Manafort committed crimes. We are a long way from knowing whether there will be criminal prosecutions in these matters. But the mere possibility of a criminal prosecution could lead the president to invoke his authority under Article II, Section 2 of the Constitution to grant “Reprieves and Pardons for Offences against the United States.”

My research on clemency shows how chief executives have used this power, in particular the power to pardon, to halt criminal prosecutions, sometimes even before they begin.

‘For any reason at all’

The pardoning power, as Founding Father Alexander Hamilton explained, is very broad, applying even to cases of treason against the United States. As Hamilton put it, “the benign prerogative of pardoning should be as little as possible fettered or embarrassed.”

Throughout our history, courts have taken a similarly expansive view. In 1977, Florida’s State Supreme Court said that “An executive may grant a pardon for good reasons or bad, or for any reason at all, and his act is final and irrevocable.”

In 1837, the United States Supreme Court held that the president’s pardon power “extends to every offence known to the law, and may be exercised at any time after its commission,…
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Macbeth, King Lear and Trump

Courtesy of The Automatic Earth


Ford Madox Brown King Lear and Cordelia c1851

Mea culpa. Yesterday I wrote Scaramouche, Scaramouche, will you do the Fandango?, and not long after publishing it, I figured I missed the target I was going for. Not 100%, and it’s not all bad, as people’s reactions have confirmed, but…

The thing is, Trump’s nomination of Anthony Scaramucci as White House Communications Director was not the main point of my piece. Tempting, because everybody knows the Queen song, but not the main one, and it certainly shouldn’t have been the title of the piece.

So, sorry for that, and let me try to correct. The much stronger point, in my ever so humble view, that I hit on yesterday is the connection between Donald Trump and William Shakespeare. In fact, I think that from now on we should all see Trump in that light. Simply because it fits so … fittingly.

Not because I would call Trump mad, that is far too easy a view. But because his story, both as it unfolds today and in its history, has so many classic Shakespearean elements. And when we look at our world through the glasses of the ‘Old Bard’, we will see it in a different light. As in: Trump could be a man in the process of going mad. Or he could not.

Not that it’s just about Trump. Richard Nixon looks, if anything, way more Shakespeare material than Da Donald. Though, admittedly, we can oversee Nixon’s entire history, while Trump’s is ongoing (he has promise), and Shakespeare is all about development, about what happens to people as they go through what happens to them.

Macbeth and King Lear describe the trappings -and much more- of power. How power corrupts, and not only absolute power. How sociopathic character traits make people seek power, and how it -often- destroys them. But also how outside forces influence them, in -just as often- highly destructive ways.

That’s not to say that Shakespeare, if he were alive today, would have written a play about Trump. I don’t know that, we don’t. I do think he would have found it hard to stay away from Nixon, but that’s just a guess, even if…
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13-Year-Old Kid Buys $552,000 Home

Courtesy of Mish

Meet Akira Ellis a 13-year-old kid. He just bought his first piece of real estate, a $552,000 four-room one bath house in Melbourne’s Frankston.
 

Akira Ellis snapped up the 575 square metre four-bedroom, one-bathroom home in Frankston in May – when he was still 12 – and recently settled the sale.

“[Buying a house] can be quite scary, especially when it’s your first purchase and renovation – there are so many things to think about,” he told the Express Advocate.

“It’s a big investment and a mistake can cost you a lot”.

Although he hunted down and picked the property, the Gosford teenager is not alone in the venture with a fair bit of help from his parents Frank and Mychel.

Even his brother Oliver and sister Saskia chipped in some pocket money to make it a whole family affair. The pint-sized housing prodigy said he planned to ‘totally transform’ the 1970s home before renting it out and looking for his next investment.

His plans include replacing the bathroom and kitchen, updating the lights and window furnishings, changing the carpet and polishing the floorboards. Akira also wants to refresh the roof and landscape the garden to boost the property value and make it more attractive to renters.

The article mention he had “help” from his parents but it did not say how much. He did find that house himself, perhaps with help from “renovating for profit”. Akira is already looking for his next property.

What can possibly go wrong?

Mike “Mish” Shedlock.

Original article here.





Protecting the Cheaters: EU Regulators in Bed With German Auto Industry Regarding Diesel

Courtesy of Mish.

On June 14, Reuters reported Munich, Home to BMW, Considers Diesel Ban to Tackle Pollution.

Today, with strong overtones of regulators hopping in bed with industries they are supposed to regulate, EU’s Car Regulator Warns Against Diesel Ban in Cities.

Munich, home to carmaker BMW, has become the latest German city to consider banning some diesel vehicles amid “shocking” nitrogen oxide emissions in the Bavarian capital.

“As much as I would welcome avoiding such bans, I think it is just as unlikely that we can continue to do without bans in the future,” Munich mayor Dieter Reiter was quoted as saying by the Sueddeutsche Zeitung newspaper on Wednesday.

Asked about the latest nitrogen oxide readings, which the paper said violated European air quality standards well beyond busy trunk roads, the mayor said: “The results are shocking, nobody expected this.”

The scandal over rigged diesel emission tests at Volkswagen has already thrown the future of diesel engines into doubt, and has highlighted carmakers’ struggle to comply with ever stricter rules on the nitrogen oxides emissions.

Regulators in Bed With Industry?

Flash forward to today.

Banning diesel cars in European cities could hamper automakers’ ability to invest in zero-emission vehicles, the European Union’s commissioner for industry has warned the bloc’s transport ministers.

In a letter seen by Reuters, Commissioner Elzbieta Bienkowska said there would be no benefit in a collapse of the market for diesel cars and that the short-term focus should be on forcing carmakers to bring dangerous nitrogen oxide emissions into line with EU regulations.

In the letter, Bienkowska told ministers she was concerned that the latest emissions violations at Audi and Porsche were discovered by prosecutors and not Germany’s vehicle and transport authorities.

Bienkowska’s letter also called for all cars with excessively high levels of nitrogen oxide emissions to be taken of European roads, but said carmakers should act on a voluntary basis.

Experts who have seen the letter to ministers say the commissioner appeared to be bowing to carmakers’ demands.

“Her letter contained some important statements that we believe show the industry’s lobbyists have scored a big win,” Bernstein analyst Max Warburton said in a report.

Diesel Job Math

The Center for Economic Studies (CESifo) produced a report on the German diesel industry for its stated client, the


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David Rosenberg: “This Is The Single Most Important Thing For The Market Over The Next Decade”

Courtesy of Zero Hedge

Several years ago, Gluskin Sheff's superstar economist (previously at Merrill), David Rosenberg (in)famously flipped from bear to bull, predicting what amounts to a victory for the Fed: a jump in (wage) inflation, a burst in economic growth, and an overall selloff in that most deflation-dependent asset, the US Treasury. None of those happened, and while we (gently) mocked Rosie's transformation at the time, recently Rosenberg himself admitted that our skepticism was accurate, when he reverted to his bearish bias over the past year, predicting that deflation would end up winning after all.

Today, in his latest market musings chartpack, we present the key reasons why Rosenberg has never been more convinced that all those calling for an end to the secular bond bull market, are wrong and why despite the Fed's best intentions to create the impression that the global economy is stabilizing, what is about to be unleashed on the global economy is at least 5 years of accelerating deflationary pressures.

As the main catalysts for his gloomy outlook, Rosenberg lists the obvious ones, debt and deflation, but by far the most important factor that prompted Rosenberg to revert to the "dark side", the one about which Rosie says "nothing is more important than this if you are looking at what will fundamentally influence the financial markets for the next decade-plus"… is demographics.

"The first of the boomers turned 70 this past year, that 80 million proverbial pig-in-the-python in North America, and 1.5 million will be doing so each year for the next fifteen years."

That fact, Rosenberg believes, will be the single most important driver of returns over the next decade.

Below, he explains why those seeking to understand market moves and inflationary forces over the coming ten years, should first and foremost focus on demographics. Everything else will follow.

* * *

As excerpted from Lower for Longer Lingers, by David Rosenberg, July 2017:

We are back into the “lower for longer” theme — lower growth, lower inflation and lower bond yields. Each cycle, the peaks keep on going lower and lower. Just as Bank of Canada Governor Stephen Poloz warned everyone last September. To be sure, he just raised


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The Rollover Trio

Courtesy of Slope of Hope

Let's take a step back – —  a few thousand steps back, actually – – and drink in a very long view of the stock market. We'll use the S&P 500 as our observed entity. Here it is below, spanning several decades, with three major tops tinted.

0721-trio

You will notice something distinct that that third "top", which is that, unlike its green-tinted predecessors, it didn't mark a top at all. It was shaped like a top. It was timed like a top. It was just about as good a top as the market gods can create. And yet it merely preceded another 35% rise in the market in a mere eighteen months. I've marked with an arrow that fateful day, February 11, 2016, which in hindsight marked one hell of a risk-free buying opportunity.

0721-abortion

Turning the pages back on Slope, I took a look to see what kinds of things were being written. Here's an item from MPTrader which lays out precisely the same stuff I was thinking:

0721-top

Of course, that notation about "…the Fed is not actively and overtly buying assets" were like famous last words, because the central bankers of the entire planet piled in and did just that. As for myself, on February 11th 2016, I made this foolish mistake:

0721-fate

That probably marked, within moments, the precise bottom. Suffice it to say that my pledge to never show Chocolate Rain or Let 'Em Burn is quite clearly important to heed.

Of course, over in ZeroHedge, the massive top was not lost upon them either:

0721-zero

So, yeah, we permabear pornsters were all excited, and we were also dead wrong. But


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Scaramouche, Scaramouche, will you do the Fandango?

Courtesy of The Automatic Earth.


Hieronymus Bosch Adoration of the Magic c1472

So sorry to see Sean Spicer go, even if I never watch TV, so I only got snippets of his acting performances -and Melissa McCarthy’s. One of the very few SNL and other ‘comedy’ shows skids that was actually funny, in the same way that very few of the New York Times and Washington Post ‘articles’ on Trump have been actually news.

As I wrote to a friend earlier today, sure Spicer’s gone, but there’ll be other entertaining characters to replace him. Say what you will about the Trump administration, but never a dull moment. Having Mike Pence become president would kill all the fun.

Sad!

Scaramucci is a great start to phase 2. Or is that 22? The guy’s a Wall Street pawn who badmouthed Da Donald not long ago. Moreover, says a Daily Beast headline, “Anthony Scaramucci Loved Hillary, Gave to Obama, and Deleted Anti-Trump Tweets”.

Wonderful!

Now I know the White House should not really be a theater, but hey, it already is, so we might as well make the best of it. And the name Scaramucci alone carries so much promise. Not only because of the Queen line from Bohemian Rhapsody, but also because of, as Wikipedia puts it:

Scaramouch. 1660s, name of a cowardly braggart (supposed by some to represent a Spanish don) in traditional Italian comedy, from Italian Scaramuccia, literally “skirmish,” from schermire “to fence,” from a Germanic source (cf. Old High German skirmen “defend”); see skirmish (n.).

and

Scaramuccia (literally “little skirmisher”), also known as Scaramouche or Scaramouch, is a stock clown character of the Italian commedia dell’arte. The role combined characteristics of the zanni (servant) and the Capitano (masked henchman).

A cowardly braggart! There is so much promise there. And theater, tragedy, drama, entertainment. Look, that’s what Shakespeare made of politics, and many others did too, so maybe we should just get used to it. It’s not all that new, kings and queens and power hungry sociopaths have been the subjects of plays and worse for ages. When you see anything Trump, think Shakespeare. Give it the proper historical context.

Think Macbeth. Think King Lear. Think Trump.

Think:

I see a little silhouetto of a man

Scaramouche, Scaramouche, will you do


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Zero Hedge

"It Feels Like An Avalanche": China's Crackdown On Conglomerates Has Sent A "Shock Wave" Across Markets

Courtesy of ZeroHedge. View original post here.

The first to suffer Beijing's crackdown against China's private merger-crazy conglomerates, wave was the acquisitive "insurance" behemoth, Anbang, whose CEO Wu Xiaohui briefly disappeared as the Politburo made it clear that the "old way" of money laundering - via offshore deals - is no longer tolerated. Then, several weeks later and shortly after the stocks of the "...



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Phil's Favorites

A new vaccine is promising to advance the frontier of eliminating malaria

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

 

A new vaccine is promising to advance the frontier of eliminating malaria

Courtesy of Simon KariukiKenya Medical Research Institute

A malaria vaccine will be piloted in Ghana, Kenya and Malawi to assess its suitability. Siegfried Modola/Reuters.

More than 30 malaria vaccine candidates are at various stages of development. The RTS,S vaccine is at t...



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Biotech

A new vaccine is promising to advance the frontier of eliminating malaria

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

 

A new vaccine is promising to advance the frontier of eliminating malaria

Courtesy of Simon KariukiKenya Medical Research Institute

A malaria vaccine will be piloted in Ghana, Kenya and Malawi to assess its suitability. Siegfried Modola/Reuters.

More than 30 malaria vaccine candidates are at various stages of development. The RTS,S vaccine is at t...



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ValueWalk

Curreen Capital - Do I Regret Selling Those Stocks?

By VW Staff. Originally published at ValueWalk.


Curreen Capital – Do I Regret Selling Those Stocks?

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Insider Scoop

Different Market, Same Story: Subprime Auto Loan Defaults On The Rise

Courtesy of Benzinga.

Related Benzinga's Top Upgrades, Downgrades For July 18, 2017 Watch These 7 Huge Put Purchases In Thursday Trade Rel...

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Digital Currencies

Bitcoin (BTC/USD) Nears All-Time High on Spike Above Daily Chart Downchannel Resistance

Courtesy of ZeroHedge. View original post here.

Bitcoin (BTC/USD) crushed shorts yesterday, smashing above the daily chart's downchannel resistance and soaring towards the all-time high around 3000. With yesterday's massive rally, the negative weekly MACD crossover has been proved a false signal.  Odds are quite good that a sustainable longer term BTC/USD bottom was found last week, especially with ETH/USD also strongly rebounding this past week.  Some consolidation can be expected today with daily RSI and Stochastics tiring, although with daily MACD just having positive...



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Chart School

Small Caps Breakout

Courtesy of Declan.

It has taken a few days for Small Caps to make their move but today was the day the Russell 2000 joined other indices in mounting a breakout. It was a clean breakout supported by positive technical strength - putting to bed the June 'bull trap'. Watch for the second round of stop-whips with an intraday move (and recovery) below 1,430.


Other indices added to their breakouts. The S&P gapped and pushed on, backed by higher volume accumulation. Watch for a tag of upper channel resistance.

...

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Members' Corner

Why we need to act on climate change now

 

Why we need to act on climate change now

Interview with Jan Dash PhD, by Ilene Carrie, Editor at Phil’s Stock World

Jan Dash PhD is a physicist, an expert at quantitative finance and risk management, and a consultant at Bloomberg LP. In his thought-provoking book, Quantitative Finance and Risk Management, A Physicist's Approach, Jan devotes a chapter to climate change and its long-term systemic risk. In this article, Ilene interviews Jan regarding his thoughts on climate change and the way it can affect our futu...



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OpTrader

swing trading portfolio - week of July 17th, 2017

Reminder: OpTrader is available to chat with Members, comments are found below each post.

 

This post is for all our live virtual trade ideas and daily comments. Please click on "comments" below to follow our live discussion. All of our current  trades are listed in the spreadsheet below, with entry price (1/2 in and All in), and exit prices (1/3 out, 2/3 out, and All out).

We also indicate our stop, which is most of the time the "5 day moving average". All trades, unless indicated, are front-month ATM options. 

Please feel free to participate in the discussion and ask any questions you might have about this virtual portfolio, by clicking on the "comments" link right below.

To learn more about the swing trading virtual portfolio (strategy, performance, FAQ, etc.), please click here ...



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Mapping The Market

The App Economy Will Be Worth $6 Trillion in Five Years

Courtesy of Jean-Luc

This would be excellent news for AAPL and GOOG to a lesser extent although not inconsequential:

The App Economy Will Be Worth $6 Trillion in Five Years 

In five years, the app economy will be worth $6.3 trillion, up from $1.3 trillion last year, according to a report released today by app measurement company App Annie. What explains the growth? More people are spending more time and -- crucially -- more money in apps. While on average people aren't downloading many more apps, App Annie expects global app usership to nearly double to 6.3 billion people in the next five years while the time spent in apps will more than double. And, it expects the...



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Promotions

NewsWare: Watch Today's Webinar!

 

We have a great guest at today's webinar!

Bill Olsen from NewsWare will be giving us a fun and lively demonstration of the advantages that real-time news provides. NewsWare is a market intelligence tool for news. In today's data driven markets, it is truly beneficial to have a tool that delivers access to the professional sources where you can obtain the facts in real time.

Join our webinar, free, it's open to all. 

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Kimble Charting Solutions

Brazil; Waterfall in prices starting? Impact U.S.?

Courtesy of Chris Kimble.

Below looks at the Brazil ETF (EWZ) over the last decade. The rally over the past year has it facing a critical level, from a Power of the Pattern perspective.

CLICK ON CHART TO ENLARGE

EWZ is facing dual resistance at (1), while in a 9-year down trend of lower highs and lower lows. The counter trend rally over the past 17-months has it testing key falling resistance. Did the counter trend reflation rally just end at dual resistance???

If EWZ b...



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All About Trends

Mid-Day Update

Reminder: Harlan is available to chat with Members, comments are found below each post.

Click here for the full report.




To learn more, sign up for David's free newsletter and receive the free report from All About Trends - "How To Outperform 90% Of Wall Street With Just $500 A Week." Tell David PSW sent you. - Ilene...

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Philip R. Davis is a founder Phil's Stock World, a stock and options trading site that teaches the art of options trading to newcomers and devises advanced strategies for expert traders...

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Ilene is editor and affiliate program coordinator for PSW. She manages the site market shadows, archives, more. Contact Ilene to learn about our affiliate and content sharing programs.

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