Posts Tagged ‘genetic markers’

Genetic Test Improves Weight Loss Success With Diets

This is an interesting press release from Interleukin Genetics (ILI) about a genetic test that may allow people to better match their diet to their genetics.  I admit to a bit of skepticism, but here goes: first background information about the test from Interleukin Genetics’s website, and second, the press release. – Ilene 

Weight Management Test 

Human obesity arises from the interactions of multiple genes, environmental factors and behaviors, rendering management and prevention of obesity very challenging.  According to WHO, lack in physical activity and easy availability of palatable foods are the principle modified characteristic of our modern lifestyle that has contributed a lot to the observed obesity worldwide. Despite the fact that we are all exposed to the same environment, not everyone becomes obese.  This could be attributed to individual genetic differences.  Genetics determines an individual’s susceptibility to obesity when exposed to an unfavorable environment as well as the way he/she can respond to diet and exercise. There have been multiple reports that describe the heritability of obesity and also utilize genetic association studies to identify the gene-gene, gene environment and gene-diet interactions involved in the development of obesity. These studies have identified a certain number of single nucleotide polymorphisms (SNPs) that respond to diet and/or exercise.  For example, some SNPs make some people more sensitive to the amount of fat in the diet, while others make some people more resistant to exercise-induced weight loss.

Interleukin Genetics has developed a genetic test panel in the area of Weight Management (WM), which includes the genes that have been validated as significant modifiers of body weight and responsiveness to diet and exercise.  The genes were selected from the Obesity Gene Map Database based on a comprehensive review of the existing scientific literature using very stringent selection criteria by a team of experts from genetics, nutrition, obesity and weight management areas. 

The following process was used to develop the Weight Management genetic test panel:

  1. Dr. Louis Perusse, one of the authors of the Obesity Gene Map review (4), provided a list of all genetic variations that were associated with body weight, body mass index, or body fat and had been replicated in at least three clinical studies. Out of hundreds of genes reported in the scientific literature relative to obesity, only 16 met this first criterion.
  2. A team of experts then reviewed all evidence on the 16 gene variations


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Scientists Move Closer to Understanding Why We Age

Scientists Move Closer to Understanding Why We Age

By Eben Harrell / London, courtesy of TIME 

Time waits for no man, the old truism goes, but in recent years scientists have shown that it does seem to move more slowly for some. Molecular biologists have observed that people’s cells often age at different rates, leading them to make a distinction between "chronological" and "biological age."

But the reason for the difference remains only vaguely understood. Environmental factors such as smoking, stress and regular exercise all seem to influence the rate at which our cells age. Now, for the first time, researchers have found a genetic link to cellular aging — a finding that suggests new treatments for a variety of age-related diseases and cancers. 

The field of "biological aging" has in recent years focused on the long molecules of DNA contained in human cells called chromosomes. All chromosomes have protective caps at either end called telomeres. Each time a cell replicates itself (as it does before it dies), the telomeres shorten, like plastic tips fraying on the end of shoelace. Shortened telomeres have been linked to a host of age-related illnesses such as heart disease and certain cancers. (Scientists have yet to study whether telomeres influence a person’s appearance). Last year’s Nobel prize in medicine was awarded to three American scientists for their work in the field, and many scientists now believe telomeres are the closest we may come to identifying a biological clock — and our best bet for one day learning how to stop or turn back that clock. 

To better understand the aging discrepancy, a team of researchers in Britain and The Netherlands scanned more than 500,000 genetic variations across the human genome. Using a population of nearly 12,000, they then attempted to pinpoint a genetic link to telomere length. (See how to prevent illness at any age.) 

In a significant breakthrough, the team successfully identified that a particular gene sequence was associated with differences in telomere length between individuals. What’s more, the sequence was clustered near a gene called TERC, which is already known to play a role in the production of an enzyme called telomerase. Telomerase repairs telomeres when they shorten. "That was very exciting for us," says Professor Nilesh Samani, a cardiologist at the University of Leicester who co-led the research, published last week in Nature Genetics. "It gave us great…
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How burnout is plaguing doctors and harming patients

 

How burnout is plaguing doctors and harming patients

Courtesy of Jay DesaiUniversity of Southern California

Exhaustion and burnout among physicians are growing problems. wavebreakmedia/Shutterstock.com

The presidential symposium at this year’s Annual Meeting of the Child Neurology Society of America in early October in Kansas City raised many eyebrows. The first presentation of this symposium focused on burnout rates among neurologists around the country.

Many of my colleagues f...



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Zero Hedge

It's Official: Bitcoin Surpasses "Tulip Mania", Is Now The Biggest Bubble In World History

Courtesy of ZeroHedge. View original post here.

One month ago, a chart from Convoy Investments went viral for showing that among all of the world's most famous asset bubbles, bitcoin was only lagging the infamous 17th century "Tulip Mania."

One month later, the price of bitcoin has exploded even higher, and so it is time to refresh where in the global bubble race bitcoin now stands, and also whether it has finally surpassed "Tulips."

Conveniently, overnight the former Bridgewater analysts Howard Wang and Robert Wu who make up C...



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Insider Scoop

7 Stocks To Watch For December 12, 2017

Courtesy of Benzinga.

Some of the stocks that may grab investor focus today are:

  • Casey's General Stores Inc (NASDAQ: CASY) reported weaker-than-expected earnings for its second quarter. Casey's shares dropped 3.62 percent to $116.86 in the after-hours trading session.
  • KMG Chemicals, Inc. (NYSE: KMG) reported upbeat results for its first quarter on Monday. KMG Che...


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Digital Currencies

No, Bitcoin Won't Boil The Oceans

Courtesy of ZeroHedge. View original post here.

Authored by Elaine Ou via Bloomberg.com,

Concerns about the cryptocurrency's energy use are overblown...

While much of the world marvels at bitcoin’s meteoric rise, another part is focused on an environmental byproduct:

The sheer amount of electricity that crypto-currencies use.

By some estimates, bitcoin’s consumption ...



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Chart School

Weekly Market Recap Dec 10, 2017

Courtesy of Blain.

Before we talk about the stodgy ole stock market, anyone see that Bitcoin?  $11K last week – $16K this week…. and as I write this bitcoin futures are up over $18K. Just another week in the life…. (here is what you need to know about bitcoin futures)

Back to your regularly scheduled program… the S&P 500 rested a bit while a small correction rolled through the massive winners of 2017 in mega cap tech land, but in the end all was well again by Friday.

“The Nasdaq Composite Index was getting a little frothy, so it&...



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Biotech

DNA has gone digital - what could possibly go wrong?

Reminder: Pharmboy and Ilene are available to chat with Members, comments are found below each post.

 

DNA has gone digital – what could possibly go wrong?

Courtesy of Jenna E. GallegosColorado State University and Jean PeccoudColorado State University

Modern advances come with new liabilities. Sergey ...



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ValueWalk

Tax Bill May Spark Exodus From High-Tax States

Courtesy of FinancialSense.com via ValueWalk.com

The following is a summary of our recent podcast, “Exodus – The Major Wealth Migration,” which can be listened to on our site here on on iTunes here.

It’s looking increasingl...



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Members' Corner

An Interview with David Brin

Our guest David Brin is an astrophysicist, technology consultant, and best-selling author who speaks, writes, and advises on a range of topics including national defense, creativity, and space exploration. He is also a well-known and influential futurist (one of four “World's Best Futurists,” according to The Urban Developer), and it is his ideas on the future, specifically the future of civilization, that I hope to learn about here.   

Ilene: David, you base many of your predictions of the future on a theory of historica...



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Mapping The Market

Puts things in perspective

Courtesy of Jean-Luc

Puts things in perspective:

The circles don't look to be to scale much!

...

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OpTrader

Swing trading portfolio - week of September 11th, 2017

Reminder: OpTrader is available to chat with Members, comments are found below each post.

 

This post is for all our live virtual trade ideas and daily comments. Please click on "comments" below to follow our live discussion. All of our current  trades are listed in the spreadsheet below, with entry price (1/2 in and All in), and exit prices (1/3 out, 2/3 out, and All out).

We also indicate our stop, which is most of the time the "5 day moving average". All trades, unless indicated, are front-month ATM options. 

Please feel free to participate in the discussion and ask any questions you might have about this virtual portfolio, by clicking on the "comments" link right below.

To learn more about the swing trading virtual portfolio (strategy, performance, FAQ, etc.), please click here ...



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Promotions

NewsWare: Watch Today's Webinar!

 

We have a great guest at today's webinar!

Bill Olsen from NewsWare will be giving us a fun and lively demonstration of the advantages that real-time news provides. NewsWare is a market intelligence tool for news. In today's data driven markets, it is truly beneficial to have a tool that delivers access to the professional sources where you can obtain the facts in real time.

Join our webinar, free, it's open to all. 

Just click here at 1 pm est and join in!

[For more information on NewsWare, click here. For a list of prices: NewsWar...



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Kimble Charting Solutions

Brazil; Waterfall in prices starting? Impact U.S.?

Courtesy of Chris Kimble.

Below looks at the Brazil ETF (EWZ) over the last decade. The rally over the past year has it facing a critical level, from a Power of the Pattern perspective.

CLICK ON CHART TO ENLARGE

EWZ is facing dual resistance at (1), while in a 9-year down trend of lower highs and lower lows. The counter trend rally over the past 17-months has it testing key falling resistance. Did the counter trend reflation rally just end at dual resistance???

If EWZ b...



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All About Trends

Mid-Day Update

Reminder: Harlan is available to chat with Members, comments are found below each post.

Click here for the full report.




To learn more, sign up for David's free newsletter and receive the free report from All About Trends - "How To Outperform 90% Of Wall Street With Just $500 A Week." Tell David PSW sent you. - Ilene...

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