Posts Tagged ‘genetic markers’

Genetic Test Improves Weight Loss Success With Diets

This is an interesting press release from Interleukin Genetics (ILI) about a genetic test that may allow people to better match their diet to their genetics.  I admit to a bit of skepticism, but here goes: first background information about the test from Interleukin Genetics’s website, and second, the press release. – Ilene 

Weight Management Test 

Human obesity arises from the interactions of multiple genes, environmental factors and behaviors, rendering management and prevention of obesity very challenging.  According to WHO, lack in physical activity and easy availability of palatable foods are the principle modified characteristic of our modern lifestyle that has contributed a lot to the observed obesity worldwide. Despite the fact that we are all exposed to the same environment, not everyone becomes obese.  This could be attributed to individual genetic differences.  Genetics determines an individual’s susceptibility to obesity when exposed to an unfavorable environment as well as the way he/she can respond to diet and exercise. There have been multiple reports that describe the heritability of obesity and also utilize genetic association studies to identify the gene-gene, gene environment and gene-diet interactions involved in the development of obesity. These studies have identified a certain number of single nucleotide polymorphisms (SNPs) that respond to diet and/or exercise.  For example, some SNPs make some people more sensitive to the amount of fat in the diet, while others make some people more resistant to exercise-induced weight loss.

Interleukin Genetics has developed a genetic test panel in the area of Weight Management (WM), which includes the genes that have been validated as significant modifiers of body weight and responsiveness to diet and exercise.  The genes were selected from the Obesity Gene Map Database based on a comprehensive review of the existing scientific literature using very stringent selection criteria by a team of experts from genetics, nutrition, obesity and weight management areas. 

The following process was used to develop the Weight Management genetic test panel:

  1. Dr. Louis Perusse, one of the authors of the Obesity Gene Map review (4), provided a list of all genetic variations that were associated with body weight, body mass index, or body fat and had been replicated in at least three clinical studies. Out of hundreds of genes reported in the scientific literature relative to obesity, only 16 met this first criterion.
  2. A team of experts then reviewed all evidence on the 16 gene variations


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Scientists Move Closer to Understanding Why We Age

Scientists Move Closer to Understanding Why We Age

By Eben Harrell / London, courtesy of TIME 

Time waits for no man, the old truism goes, but in recent years scientists have shown that it does seem to move more slowly for some. Molecular biologists have observed that people’s cells often age at different rates, leading them to make a distinction between "chronological" and "biological age."

But the reason for the difference remains only vaguely understood. Environmental factors such as smoking, stress and regular exercise all seem to influence the rate at which our cells age. Now, for the first time, researchers have found a genetic link to cellular aging — a finding that suggests new treatments for a variety of age-related diseases and cancers. 

The field of "biological aging" has in recent years focused on the long molecules of DNA contained in human cells called chromosomes. All chromosomes have protective caps at either end called telomeres. Each time a cell replicates itself (as it does before it dies), the telomeres shorten, like plastic tips fraying on the end of shoelace. Shortened telomeres have been linked to a host of age-related illnesses such as heart disease and certain cancers. (Scientists have yet to study whether telomeres influence a person’s appearance). Last year’s Nobel prize in medicine was awarded to three American scientists for their work in the field, and many scientists now believe telomeres are the closest we may come to identifying a biological clock — and our best bet for one day learning how to stop or turn back that clock. 

To better understand the aging discrepancy, a team of researchers in Britain and The Netherlands scanned more than 500,000 genetic variations across the human genome. Using a population of nearly 12,000, they then attempted to pinpoint a genetic link to telomere length. (See how to prevent illness at any age.) 

In a significant breakthrough, the team successfully identified that a particular gene sequence was associated with differences in telomere length between individuals. What’s more, the sequence was clustered near a gene called TERC, which is already known to play a role in the production of an enzyme called telomerase. Telomerase repairs telomeres when they shorten. "That was very exciting for us," says Professor Nilesh Samani, a cardiologist at the University of Leicester who co-led the research, published last week in Nature Genetics. "It gave us great…
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And America's Dirtiest Metropolis Is...

Courtesy of Zero Hedge

Well, you guessed it, New York City of course - this dirty city has more pests and litter than any other large metropolis in the United States, according to newly compiled government data by the cleaning-services company Busy Bee.

The cleaning company ranked 40 large cities across the United States based on data from the Environmental Protection Agency (EPA), the American Housing Survey (AHS), and the U.S. Census Bureau to create an informative infographic to determine just how shitty America really is. Factors include litter, pests such as mice and cockroaches, population density, particulate matter a...



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Zero Hedge

And America's Dirtiest Metropolis Is...

Courtesy of Zero Hedge

Well, you guessed it, New York City of course - this dirty city has more pests and litter than any other large metropolis in the United States, according to newly compiled government data by the cleaning-services company Busy Bee.

The cleaning company ranked 40 large cities across the United States based on data from the Environmental Protection Agency (EPA), the American Housing Survey (AHS), and the U.S. Census Bureau to create an informative infographic to determine just how shitty America really is. Factors include litter, pests such as mice and cockroaches, population density, particulate matter a...



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ValueWalk

Is College Really for All?

By The Foundation for Economic Education. Originally published at ValueWalk.

In the last two and a half generations, the number of students who go on to attend college, as a percentage of the population, has tripled. In 1959, about 20 percent of high school students went on to college. Since relatively few people were earning degrees, having one all but guaranteed getting a good, high-paying job. As a result, parents, high schools, and colleges began encouraging more and more high school students to go to college. Today, about 60 percent of high school students go on to college. But has the big push to get kids into college done anything to improve outcomes? Is the average $250,000 investment in a four-year degree at all worth it? If not, what alternatives exist? Join Antony Davies and James Harrigan as they talk about this and more on this week’s episode of Words and Num...



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Insider Scoop

Imperial Capital: MINDBODY Has The Keys To Success

Courtesy of Benzinga.

Related 7 Stocks Moving In Wednesday's After-Hours Session 50 Biggest Movers From Friday ...

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Digital Currencies

US Olympians Are Turning To Bitcoin To Offset Competition-Related Costs

Courtesy of ZeroHedge. View original post here.

As many college athletes know all too well, funding for more niche sports like - for example - luge is often lacking, and securing more often requires hours of fundraising by the team's boosters.

Which is why, ahead of the Winter Games in PyeongChang, some teams started getting creative. For instance, fundraisers for the US luge team have started accepting donations in bitcoin. Indeed, the team has raised several thousand dollars worth of bitcoin.

...



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Chart School

'Bull Trap' in Dow Jones Industrial Average

Courtesy of Declan.

Starting to see evidence that the February bounce in markets is fading. The Dow Jones Industrial Average finished with a 'bull trap' as it ducked below breakout support despite finishing above yesterday's close. Volume dropped as relative performance against tech indices took a marked step lower. Troubling times for the 'flight-to-safety' route.


The Semiconductor Index had looked like it was ready to mount a challenge of the January 'bull trap' but the last couple of days have seen a second attempt at a reversal ...

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Biotech

What is 'right to try,' and could it help?

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

 

What is 'right to try,' and could it help?

In this March 18, 2011 photo, Cassidy Hempel waved at hospital staff as she was being treated for a rare disorder. Her mother Chris, left, fought to gain permission for an experimental drug. AP Photo/Marcio Jose Sanchez

Morten Wendelbo, Texas A&M University and Timothy Callaghan, ...



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Mapping The Market

The tricks propagandists use to beat science

Via Jean-Luc

How propagandist beat science – they did it for the tobacco industry and now it's in favor of the energy companies:

The tricks propagandists use to beat science

The original tobacco strategy involved several lines of attack. One of these was to fund research that supported the industry and then publish only the results that fit the required narrative. “For instance, in 1954 the TIRC distributed a pamphlet entitled ‘A Scientific Perspective on the Cigarette Controversy’ to nearly 200,000 doctors, journalists, and policy-makers, in which they emphasized favorable research and questioned results supporting the contrary view,” say Weatherall and co, who call this approach biased production.

A second approach promoted independent research that happened to support ...



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Members' Corner

An Interview with David Brin

Our guest David Brin is an astrophysicist, technology consultant, and best-selling author who speaks, writes, and advises on a range of topics including national defense, creativity, and space exploration. He is also a well-known and influential futurist (one of four “World's Best Futurists,” according to The Urban Developer), and it is his ideas on the future, specifically the future of civilization, that I hope to learn about here.   

Ilene: David, you base many of your predictions of the future on a theory of historica...



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OpTrader

Swing trading portfolio - week of September 11th, 2017

Reminder: OpTrader is available to chat with Members, comments are found below each post.

 

This post is for all our live virtual trade ideas and daily comments. Please click on "comments" below to follow our live discussion. All of our current  trades are listed in the spreadsheet below, with entry price (1/2 in and All in), and exit prices (1/3 out, 2/3 out, and All out).

We also indicate our stop, which is most of the time the "5 day moving average". All trades, unless indicated, are front-month ATM options. 

Please feel free to participate in the discussion and ask any questions you might have about this virtual portfolio, by clicking on the "comments" link right below.

To learn more about the swing trading virtual portfolio (strategy, performance, FAQ, etc.), please click here ...



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Promotions

NewsWare: Watch Today's Webinar!

 

We have a great guest at today's webinar!

Bill Olsen from NewsWare will be giving us a fun and lively demonstration of the advantages that real-time news provides. NewsWare is a market intelligence tool for news. In today's data driven markets, it is truly beneficial to have a tool that delivers access to the professional sources where you can obtain the facts in real time.

Join our webinar, free, it's open to all. 

Just click here at 1 pm est and join in!

[For more information on NewsWare, click here. For a list of prices: NewsWar...



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Kimble Charting Solutions

Brazil; Waterfall in prices starting? Impact U.S.?

Courtesy of Chris Kimble.

Below looks at the Brazil ETF (EWZ) over the last decade. The rally over the past year has it facing a critical level, from a Power of the Pattern perspective.

CLICK ON CHART TO ENLARGE

EWZ is facing dual resistance at (1), while in a 9-year down trend of lower highs and lower lows. The counter trend rally over the past 17-months has it testing key falling resistance. Did the counter trend reflation rally just end at dual resistance???

If EWZ b...



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All About Trends

Mid-Day Update

Reminder: Harlan is available to chat with Members, comments are found below each post.

Click here for the full report.




To learn more, sign up for David's free newsletter and receive the free report from All About Trends - "How To Outperform 90% Of Wall Street With Just $500 A Week." Tell David PSW sent you. - Ilene...

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Philip R. Davis is a founder Phil's Stock World, a stock and options trading site that teaches the art of options trading to newcomers and devises advanced strategies for expert traders...

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Ilene is editor and affiliate program coordinator for PSW. She manages the site market shadows, archives, more. Contact Ilene to learn about our affiliate and content sharing programs.

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