Archive for 2014

Comment by Pharmboy

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  1. Pharmboy

    Simply the best place to take stem cells is from a furtilized egg that has differentiated enough in vitro (in a test tube), but is not implanted.  These cells can then be separated and differentiated to several different cell types.  That is the controversy. 
     
    The real challenge is to put in the right ‘things’ that help these cells turn into kidney, lung, liver, neurons, etc. 







Comment by ilene

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  1. ilene

    Bush restricted the use of embryonic stem cells to about 60 (the entry below from wiki says 21) cell lines, and there were problems with many of those cell lines. Whether the federal government is funding stem cell research is one issue, but if it is, then I believe it should fund it across the board and allow the scientists doing the research to decide which cells they are going to use.  

    This is from Wikipedia:   President Bush announced, on August 9, 2001 that federal funds, for the first time, would be made available for hESC research on currently existing embryonic stem cell lines. President Bush authorized research on existing human embryonic stem cell lines, not on human embryos under a specific, unrealistic timeline in which the stem cell lines must have been developed. However, the Bush Administration chose not to permit taxpayer funding for research on hESC cell lines not currently in existence, thus limiting federal funding to research in which "the life-and-death decision has already been made".[34] The Bush Administration’s guidelines differ from the Clinton Administration guidelines which did not distinguish between currently existing and not-yet-existing hESC. Both the Bush and Clinton guidelines agree that the federal government should not fund hESC research that directly destroys embryos…

    [edit]U.S. Congressional response

    In April 2004, 206 members of Congress signed a letter urging President Bush to expand federal funding of embryonic stem cell research beyond what Bush had already supported.

    In May 2005, the House of Representatives voted 238-194 to loosen the limitations on federally funded embryonic stem-cell research — by allowing government-funded research on surplus frozen embryos from in vitro fertilization clinics to be used for stem cell research with the permission of donors — despite Bush’s promise to veto the bill if passed.[36] On July 29, 2005, Senate Majority Leader William H. Frist (R-TN), announced that he too favored loosening restrictions on federal funding of embryonic stem cell research.


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Comment by ilene

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  1. ilene

    Okay, that was weird – I now see all the attempted posts that didn’t show up last night, so I deleted the excess ones.

    Questions for Pharmboy:

    1) Will removing the ban help researchers now – i.e. will many choose to work with previously disallowed cell lines?
    2) I was going to ask if there are any interesting investments in any of these areas currently that you know of off-hand? (Not a research assignment, just in general).
    3) My feeling with stem cells – and this is just hypothetical since I’ve never worked with them or even read much about the details – is that the more genetic manipulation involved in getting the cells to where you want them, from their original state, the more problems and unforeseen events to go wrong. Is that true in practice? Is there any preference for not using long-standing cell lines that have been in existence for a long time?

    Thanks!

    Ilene







Comment by ilene

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  1. ilene

    I can’t post the material but here’s the link:  http://en.wikipedia.org/wiki/Stem_cell_controversy (starting at orgins, about 2/3s down the page).







Comment by humvee4me

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  1. humvee4me

    Regarding the "Ban Lifted on Federal Funding of Stem Cell Research"; it would be nice to remove politics from news reporting.
      The Bush administration has been funding stem cell research on existing lines of embryonic stem cells and unlimited lines on adult stem cells.  Despite what the MSM states there has been tremendous progress on the research in the past decade.  I refer you to a CNN article from 2001
    http://archives.cnn.com/2001/ALLPOLITICS/08/09/stem.cell.bush/







Comment by Pharmboy

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  1. Pharmboy

    Ilene – to answer your questions:
    1.  I believe so, although I am not a law expert.
    2.  There are at least a half dozen companies focused on the stem cell arena, but this is an area I know little about.  Without researching the science (most of it is proprietary), it would be hard to give them a fair shake.  Any company can say they have ‘cured’ something in a rat, mouse, etc, but until they get proof in humans, it is all pie in the sky.  To me, the companies are so early in the game, much like DNA/RNA companies of 20 or so years ago where things are just starting to come out to the market e.g., ISIS.  I think what WILL explode in the coming years is medical devices and testing.  The DNA/RNA is getting smaller, faster and less expensive, so Dr.s will be able to run a simple test and know what is going on within minutes while in the office.  Cutting out the lab services companies.  I think I have noted it before on the site – anything that gets reimbursement my medicare/medicaid will do well, b’c Dr.s can charge against it and get incremental revenue.
    3.  Again, I am not an expert, so I can see things go wrong where a liver is growing in the brain, etc.  I believe though one the cells have moved down a path, then it would be very hard for them to change their course.  As for long standing cell lines, from my experience, I have used cells that have been frozen in liquid Nitrogen for > 7 yrs, and they are fine to bring out again.  Supposedly the cells will last for many, many more beyond that, so I don’t see a problem for time.  # of passages yes (by passages I mean the number of times the cells are split into new cells) but don’t know how many it is too many.







Comment by jerconn

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  1. jerconn

    We may get a better re-entry on those in any case…I think the target by earnings remains the same…







Comment by Pharmboy

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  1. Pharmboy

    Nice: Mafia is now Italy's #1 Bank.







Comment by judy

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  1. judy

    From global news:
    There has been a refitting of the S&P GSC index (Goldman Sachs Commodity Index).
    This is what has made the WTI market so treacherous of late. In the rebalancing,
    WTI will fall to 30.25% of weight from 32.59%. Brent on the other hand shall rise t
    o 17.35% from 15.9%. We are talking billions of dollar in position changes without m
    uch concern for who is in the way.







Comment by pstas

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  1. pstas

    CMG- Phil, you outlined a trade earlier this morning for Yodi- sell Jan 345 calls and buy Mar put spread 320/300.
    You indicated net .10 on the total spread but also indicated "no margin". Not disagreeing on the trade but my screen does not indicate that. What am I missing?







 
 
 

Zero Hedge

Americans' Economic Hope Has Collapsed

Courtesy of ZeroHedge. View original post here.

Which came first, the confidence or the stock market rally?

One thing is for sure, the crash in stocks in December has crushed the hope of Americans that their economic future is going to be better under President Trump.

Overall confidence dipped to 58.1 - a 4-month low, but, U.S. consumers this month were the most downbeat on the economy since November 2016, a third straight drop after expectations reached a 16-year high just three months earlier, as the partial government shutdown wears on toward a fourth week.

...



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Kimble Charting Solutions

Triple Breakout Test In Play For S&P 500!

Courtesy of Chris Kimble.

Is the rally of late about to run out of steam or is a major breakout about to take place in the S&P 500? What happens at current prices should go a long way in determining this question.

This chart looks at the equal weight S&P 500 ETF (RSP) on a daily basis over the past 15-months.

The rally from the lows on Christmas Eve has RSP testing the top of a newly formed falling channel while testing the underneath side of the 2018 trading range and its falling 50-day moving average at (1).

At this time RPS is facing a triple resistance test. Wil...



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Phil's Favorites

Brexit deal flops, Theresa May survives -- so what happens now?

 

Brexit deal flops, Theresa May survives -- so what happens now?

Courtesy of Victoria Honeyman, University of Leeds

As the clock ticks down to March 29 2019, all of the political manoeuvring, negotiating, arguing and fighting is coming to a peak. In the two and a half years since the 2016 EU referendum, views on both sides have hardened and agreement still seems as far away as it was the day after the referendum.

With Theresa May’s withdrawal agreement disliked by all sides, and voted down by an unprecedented majority in the House of Commons, everyone is wondering what can and should be done next?

...



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Digital Currencies

Crypto-Bubble: Will Bitcoin Bottom In February Or Has It Already?

Courtesy of Michelle Jones via ValueWalk.com

The new year has been relatively good for the price of bitcoin after a spectacular collapse of the cryptocurrency bubble in 2018. It’s up notably since the middle of December and traded around the psychological level of $4,000... so is this a sign that the crypto market is about to recover?

Of course, it depends on who you ask, but one analyst discovered a pattern which might point to a bottom next month.

A year after the cryptocurrency bubble popped

CCN...



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ValueWalk

D.E. Shaw Investment Calls For Leadership Change At EQT

By ActivistInsight. Originally published at ValueWalk.

Elliott Management has offered to acquire QEP Resources for approximately $2.1 billion, contending the oil and gas explorer’s turnaround efforts have done little to lift the company’s share price. The company responded and said that a thorough review of the proposition is imperative in order to properly act in the best interests of shareholders, “taking into account the company’s other alternatives and current market conditions.” The news came only a month after Travelport Worldwide agreed to sell itself to Siris Capital Group and Elliott’s private equity arm Evergreen Coast Capital for $4.4 billion in cash and two months after Athenahealth was bought by Veritas and Evergreen for $5.7 bi...



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Insider Scoop

UBS Says Disney's Streaming Ambition Gives It A 'New Hope'

Courtesy of Benzinga.

Related DIS Despite Some Risks, Analysts Still Expecting Double Digit Growth From Communications Services In Q4 ...

http://www.insidercow.com/ more from Insider

Chart School

Weekly Market Recap Jan 13, 2019

Courtesy of Blain.

In last week’s recap we asked:  “Has the Fed solved all the market’s problems in 1 speech?”

Thus far the market says yes!  As Guns n Roses preached – all we need is a little “patience”.  Four up days followed by a nominal down day Friday had the market following it’s normal pattern the past nearly 30 years – jumping whenever the Federal Reserve hints (or essentially says outright) it is here for the markets.   And in case you missed it the prior Friday, Chairman Powell came back out Thursday to reiterate the news – so…so… so… patient!

Fed Chairman Jerome Powell reinforced that message Thursday during a discussion at the Economic Club of Washington where he said that the central bank will be “fle...



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Members' Corner

Why Trump Can't Learn

 

Bill Eddy (lawyer, therapist, author) predicted Trump's chaotic presidency based on his high-conflict personality, which was evident years ago. This post, written in 2017, references a prescient article Bill wrote before Trump even became president, 5 Reasons Trump Can’t Learn. ~ Ilene 

Why Trump Can’t Learn

Donald Trump by Gage Skidmore (...



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Biotech

Opening Pandora's Box: Gene editing and its consequences

Reminder: We are available to chat with Members, comments are found below each post.

 

Opening Pandora's Box: Gene editing and its consequences

Bacteriophage viruses infecting bacterial cells , Bacterial viruses. from www.shutterstock.com

Courtesy of John Bergeron, McGill University

Today, the scientific community is aghast at the prospect of gene editing to create “designer” humans. Gene editing may be of greater consequence than climate change, or even the consequences of unleashing the energy of the atom.

...

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Mapping The Market

Trump: "I Won't Be Here" When It Blows Up

By Jean-Luc

Maybe we should simply try him for treason right now:

Trump on Coming Debt Crisis: ‘I Won’t Be Here’ When It Blows Up

The president thinks the balancing of the nation’s books is going to, ultimately, be a future president’s problem.

By Asawin Suebsaeng and Lachlan Markay, Daily Beast

The friction came to a head in early 2017 when senior officials offered Trump charts and graphics laying out the numbers and showing a “hockey stick” spike in the nationa...



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OpTrader

Swing trading portfolio - week of September 11th, 2017

Reminder: OpTrader is available to chat with Members, comments are found below each post.

 

This post is for all our live virtual trade ideas and daily comments. Please click on "comments" below to follow our live discussion. All of our current  trades are listed in the spreadsheet below, with entry price (1/2 in and All in), and exit prices (1/3 out, 2/3 out, and All out).

We also indicate our stop, which is most of the time the "5 day moving average". All trades, unless indicated, are front-month ATM options. 

Please feel free to participate in the discussion and ask any questions you might have about this virtual portfolio, by clicking on the "comments" link right below.

To learn more about the swing trading virtual portfolio (strategy, performance, FAQ, etc.), please click here ...



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Promotions

Free eBook - "My Top Strategies for 2017"

 

 

Here's a free ebook for you to check out! 

Phil has a chapter in a newly-released eBook that we think you’ll enjoy.

In My Top Strategies for 2017, Phil's chapter is Secret Santa’s Inflation Hedges for 2017.

This chapter isn’t about risk or leverage. Phil present a few smart, practical ideas you can use as a hedge against inflation as well as hedging strategies designed to assist you in staying ahead of the markets.

Some other great content in this free eBook includes:

 

·       How 2017 Will Affect Oil, the US Dollar and the European Union

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About Phil:

Philip R. Davis is a founder Phil's Stock World, a stock and options trading site that teaches the art of options trading to newcomers and devises advanced strategies for expert traders...

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About Ilene:

Ilene is editor and affiliate program coordinator for PSW. She manages the site market shadows, archives, more. Contact Ilene to learn about our affiliate and content sharing programs.

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