Posts Tagged ‘prostate cancer’

Take On The Prostate

Over a decade ago, I did some research in the area of PSA testing and prostate cancer, so this field is a personal interest of mine. My impression from reading the NY Times article, The Great Prostate Mistake, by the pathologist who discovered the test, is that questions being asked in the nineties are being answered more and more in the negative.   

In the large study I worked on, we found that lowering the threshold level of PSA deemed worrisome in younger men resulted in more positive biopsies, including biopsies with apparently significant higher grade/aggressive cancer, but whether or not treating those cancer had overall beneficial results wasn’t known or determined.  This illustrates a common dilemma in medical science – what happens when detection methods advance before sufficient evidence exists as to the risks and rewards of potential treatment options? The goal shouldn’t be to simply find cancer, but to promote a healthful life.  The words "do no harm" are particularly meaningful.  With that, let’s move on to the thoughts of John Wrenn MD, a practicing urologist who sent me the NY Times article along with his thoughts on the subject.  - Ilene 

My Take On The Prostate

Courtesy of John Wrenn, MD

   As a urologist, I make a lot of my living off of prostate health and certainly have concerns about over testing, over diagnosis and over treatment.  The biggest question remains, in my opinion, who to treat more than anything else. I think PSA screening is probably on par with Mammograms and cholesterol testing as far as questionable value is concerned. Colonoscopy doesn’t seem as dubious largely because colon cancer tends to have fewer gray areas as to who needs treatment, and while invasive, screening for colon cancer doesn’t lead a significant portion of patients with positive findings to treatments that only make a difference in cancer specific survival for a few, while causing life altering functional changes in many. 

 

   I am still not sure that America is ready to return to a medical system where treatment is only given when the disease becomes symptomatic or grossly detectible, although the outcomes would probably be only marginally different
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Top 10 Medical Breakthroughs

Interesting list on medical breakthoughs – with my comments in red. – Ilene

TIME’s Top 10 Medical Breakthroughs

By Alice Park at TIME

stem cell created mouse - TIME And the top ten are:

  1. New Mammography Guidelines
  2. AIDS Vaccine
  3. Funding Ban Lifted on Stem-Cell Research
  4. H1N1 Vaccine
  5. Stem-Cell-Created Mice
  6. Prostate-Cancer Screening
  7. New Research on Autism
  8. New Drug for Osteoporosis
  9. New Alzheimer’s Genes
  10. Brown Fat in Adults 
*****

New Mammography Guidelines

It usually takes a Washington scandal to put the discussion of women’s breasts on political agendas, but in November it was a routine update of breast-cancer-screening guidelines by a government panel of medical advisers that stirred up a furor. Based on new calculations weighing the risks and benefits of routine screening, the U.S. Preventive Services Task Force’s new recommendations advised women to begin routine mammograms at age 50 instead of 40 and to switch from yearly to biennial screenings; it also advised women to eliminate breast self-exams altogether… 

That might be a bit of a relief to those of us who have been less than perfect in following the previous requirements, these new ones may be easier and less guilt-generating.  And we all know stress is unhealthy.  

AIDS Vaccine

In a field that has seen more failure than success, experts received the news of an effective new AIDS vaccine with a fair share of skepticism…

31% effective – but that’s about as good as it gets so far.  

Funding Ban Lifted on Stem-Cell Research

It was eight years in coming — which felt like eons to some researchers — but on March 9, President Obama rescinded his predecessor’s Executive Order prohibiting the use of federal money to fund research on stem cells. A congressional law still prevents scientists from using government funds to create new lines of embryonic stem cells,..

The less politics is involved with science the better, maybe now we can move on? 

H1N1 Vaccine

…In many places around the country, there was not enough vaccine even to cover members of priority groups targeted by the government, including young children, pregnant women, health care workers, parents of infants younger than 6 months and those with underlying conditions such as asthma or diabetes. And yet according to the latest polls, 55% of Americans said they would not get the new vaccine — which was created and tested in record time after H1N1 first appeared last


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Chart School

Price and Volume Swing Analysis on Bitcoin and Silver

Courtesy of Read the Ticker

Many take guidance from news, pundits or advisors. Well sometimes the swings of price and volume are a better measure of what happens next.

The big boys do not accumulate or distribute in single 1 second trade, they build positions over weeks, months and years. They use price swings in the market to build or reduce positions, and you can see their intent by studying swings of price and volume and applying Tim Ord logic as written in his book called 'The Secret Science of Price and Volume: Techniques for Spotting Market Trends, Hot Sectors, and the Best Stocks'.

Tim Ord is a follower of Richard Wyckoff logic, his book has added to the studies of Richard Wyckoff, Richard Ney and Bob Evans.

Richard Wyckoff after years of...

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Phil's Favorites

60/40 is Dead. Again.

 

60/40 is Dead. Again.

Courtesy of 

Doing nothing has been one of the best strategies of the last few decades.

I’m talking about the tried and true 60/40 portfolio. 60% stocks. 40% bonds. You had to rebalance, so not exactly nothing, but as close to it as you can get.

Nothing and easy, however, aren’t the same thing. You had to sit through multiple 50% crashes in the stock market. You had to sit on your hands during periods where “everyone” was getting rich. On the spectrum of easy to impossible, doing “nothing” is closer to the latter.

How many people can stay the course for multiple decades? The investor’s principal challenge is to fight the urge to de-risk in a bear market and add risk in a bul...



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Zero Hedge

Ethereum's Turn To Outshine Bitcoin Is Coming, UBS Says

Courtesy of ZeroHedge View original post here.

After a stellar start to the year, which saw its price soar to an all time high above $4,100, trouncing virtually all of its crypto peers, Ethereum has stagnated in recent weeks, with its place in the spotlight taken by bitcoin whose impressive outperformance has been the result of now confirmed speculation that a bitcoin futures ETF is coming. It also meant that what has traditionally been a close correlation between the two largest cryptos has broken in favor of the larger peer; it would also suggest that ethereum is trading about $1000 cheap vs bitcoin.

...



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Digital Currencies

Ethereum's Turn To Outshine Bitcoin Is Coming, UBS Says

Courtesy of ZeroHedge View original post here.

After a stellar start to the year, which saw its price soar to an all time high above $4,100, trouncing virtually all of its crypto peers, Ethereum has stagnated in recent weeks, with its place in the spotlight taken by bitcoin whose impressive outperformance has been the result of now confirmed speculation that a bitcoin futures ETF is coming. It also meant that what has traditionally been a close correlation between the two largest cryptos has broken in favor of the larger peer; it would also suggest that ethereum is trading about $1000 cheap vs bitcoin.

...



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Politics

Steve Bannon faces criminal charges over Jan. 6 panel snub, setting up a showdown over executive privilege

 

Steve Bannon faces criminal charges over Jan. 6 panel snub, setting up a showdown over executive privilege

Defiant or following Trump’s direction? John Lamparski/NurPhoto via Getty Images

Courtesy of Kirsten Carlson, Wayne State University

The House committee investigating the Jan. 6 attack on the U.S. Capitol is tasked with providing as full an account as possible of the attempted insurrection. But there is a problem: Not everyone is cooperating.

As of Oct. 14, 2021, Steve Bannon, a one-tim...



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Biotech/COVID-19

Ivermectin is a Nobel Prize-winning wonder drug - but not for COVID-19

 

Ivermectin is a Nobel Prize-winning wonder drug – but not for COVID-19

While ivermectin was originally used to treat river blindness, it has also been repurposed to treat other human parasitic infections. ISSOUF SANOGO/AFP via Getty Images

Courtesy of Jeffrey R. Aeschlimann, University of Connecticut

Ivermectin is an over 30-year-old wonder drug that treats life- and sight-threatening parasitic infections. Its lasting influence on global health has been so profound...



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Promotions

Phil's Interview on Options Trading with TD Bank

TD Bank's host Bryan Rogers interviewed Phil on June 10 as part of TD's Options Education Month. If you missed the program, be sure to watch the video below. It should be required viewing for anyone trading or thinking about trading using options. 

Watch here:

TD's webinar with Phil (link) or right here at PSW

Screenshots of TD's slides illustrating Phil's examples:

 

 

&n...



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Kimble Charting Solutions

Crude Oil Cleared For Blast Off On This Dual Breakout?

Courtesy of Chris Kimble

Is Crude Oil about to blast off and hit much higher prices? It might be worth being aware of what could be taking place this month in this important commodity!

Crude Oil has created lower highs over the past 13-years, since peaking back in 2008, along line (1).

It created a “Double Top at (2), then it proceeded to decline more than 60% in four months.

The countertrend rally in Crude Oil has it attempting to break above its 13-year falling resistance as well as its double top at (3).

A successful breakout at (3) would suggest Crude Oil is about to mo...



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ValueWalk

Managing Investments As A Charity Or Nonprofit

By Anna Peel. Originally published at ValueWalk.

Maintaining financial viability is a constant challenge for charities and nonprofit organizations.

Q4 2020 hedge fund letters, conferences and more

The past year has underscored that challenge. The pandemic has not just affected investment returns – it’s also had serious implications for charitable activities and the ability to fundraise. For some organizations, it’s even raised doubts about whether they can continue to operate.

Finding ways to generate long-term, sustainable returns for ...



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Mapping The Market

Suez Canal: Critical Waterway Comes to a Halt

 

Suez Canal: Critical Waterway Comes to a Halt

Courtesy of Marcus Lu, Visual Capitalist

The Suez Canal: A Critical Waterway Comes to a Halt

On March 23, 2021, a massive ship named Ever Given became lodged in the Suez Canal, completely blocking traffic in both directions. According to the Suez Canal Authority, the 1,312 foot long (400 m) container ship ran aground during a sandstorm that caused low visibility, impacting the ship’s navigation. The vessel is owned by Taiwanese shipping firm, Evergreen Marine.

With over 2...



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The Technical Traders

Adaptive Fibonacci Price Modeling System Suggests Market Peak May Be Near

Courtesy of Technical Traders

Our Adaptive Fibonacci Price Modeling system is suggesting a moderate price peak may be already setting up in the NASDAQ while the Dow Jones, S&P500, and Transportation Index continue to rally beyond the projected Fibonacci Price Expansion Levels.  This indicates that capital may be shifting away from the already lofty Technology sector and into Basic Materials, Financials, Energy, Consumer Staples, Utilities, as well as other sectors.

This type of a structural market shift indicates a move away from speculation and towards Blue Chip returns. It suggests traders and investors are expecting the US consumer to come back strong (or at least hold up the market at...



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Lee's Free Thinking

Texas, Florida, Arizona, Georgia - The Branch COVIDIANS Are Still Burning Down the House

 

Texas, Florida, Arizona, Georgia – The Branch COVIDIANS Are Still Burning Down the House

Courtesy of Lee Adler, WallStreetExaminer 

The numbers of new cases in some of the hardest hit COVID19 states have started to plateau, or even decline, over the past few days. A few pundits have noted it and concluded that it was a hopeful sign. 

Is it real or is something else going on? Like a restriction in the numbers of tests, or simply the inability to test enough, or are some people simply giving up on getting tested? Because as we all know from our dear leader, the less testing, the less...



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Insider Scoop

Economic Data Scheduled For Friday

Courtesy of Benzinga

  • Data on nonfarm payrolls and unemployment rate for March will be released at 8:30 a.m. ET.
  • US Services Purchasing Managers' Index for March is scheduled for release at 9:45 a.m. ET.
  • The ISM's non-manufacturing index for March will be released at 10:00 a.m. ET.
  • The Baker Hughes North American rig count report for the latest week is scheduled for release at 1:00 p.m. ET.
...

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About Phil:

Philip R. Davis is a founder Phil's Stock World, a stock and options trading site that teaches the art of options trading to newcomers and devises advanced strategies for expert traders...

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