Posts Tagged ‘supplements’

High doses of antioxidant supplements induce stem cell genetic abnormalities

This is interesting, and important if you’re taking lots of supplements thinking that the more antioxidants you take, the longer you’ll live. Research is providing plenty of evidence that it doesn’t work so simply, while supplements fail to act according to the logical prevailing theory. Here’s another piece. – Ilene  

High doses of antioxidant supplements induce stem cell genetic abnormalities

Spoonful of dietary supplements

Courtesy of David Granovsky, in SCIENCE & STEM CELLS 

High doses of antioxidant supplements induce stem cell genetic abnormalities

High doses of antioxidant nutritional supplements, such as vitamins C and E, can increase genetic abnormalities in cells, which may predispose supplement-takers to developing cancer, according to a new study from the Cedars-Sinai Heart Institute.

The study, led by Eduardo Marbán, M.D., Ph.D., director of the Cedars-Sinai Heart Institute, was published online today in the medical journal Stem Cells. The study also will appear in the journal’s July printed edition.

Marbán and his team accidentally discovered the danger of excessive antioxidant doses while seeking a way to reduce the genetic abnormalities that occurred naturally when the scientists sought to multiply human cardiac stem cells.

Marbán stressed that the study’s finding applies only to excessive  and not to foods that are rich in antioxidants, such as milk, oranges, blueberries and peanuts. In recent years, multiple studies have touted the benefits of foods rich in antioxidants.

“Taking one multivitamin daily is fine, but a lot of people take way too much because they think if a little is good, a lot must be better,” said Marbán, who is also the Mark Siegel Family Professor at Cedars-Sinai. “That is just not the case. If you are taking 10 or 100 times the amount in a daily multivitamin, you may be predisposing your cells to developing cancer, therefore doing yourself more harm than good.”

In laboratories, stem cells are often grown in a Petri dish culture than is composed of 20 percent oxygen, whereas cells growing inside human tissue are exposed to just 3 to 5 percent oxygen. But Marbán’s team of researchers became frustrated because the higher concentration of oxygen in lab-grown stem cells resulted in 9 percent of the cells being rejected because of genetic abnormalities.

“We sought to counter that oxidation problem by adding high doses of antioxidants directly to
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Autism: Kids put at risk

For anyone who knows children with autism, you might find this fascinating.

MED-AUTISM

I’ve seen some of this first-hand in my own search of information on autism. Some of the various treatments are worrisome on several levels. (Others are just expensive.) The results from plentiful arrays of lab tests are questionable, but used to show "chemical imbalances," which then are said to require treatment. I would question whether the results are accurate, but even more to the point, whether there is any need to "treat" these questionable lab results. Assuming some of the measures are accurate, the studies haven’t been done to assess what the results mean. The information provided is correlational information, which is not cause and effect, and certainly does not translate further to prescribing safe, effective therapies — the gap is unbelievably enormous, but routinely crossed over with hope, and a long list of supplements to buy.

After questionable lab test results are used to give diagnoses and recommend untested, unproven treatment regimens, another cause for concern is that the "treatments" are similarly untested.  So for example, even if a biochemical measure of a chemical in the blood was accurate (a generous assumption), there have been no double blind studies to show that the particular measure is in fact a problem, let alone a reason to engage in the proposed "treatment." There are no credible studies to show the treatment is effective. It could actually be harmful. The "studies" cited seem to be long lists of case reports, correlations found by blood tests (with no proven meaning), coupled with semi-scientific, semi-logical theories. The semi-scientific aspect of the process gives parents a false sense of understanding what they’re being told, because it may make sense. They don’t have the background to know what they don’t and can’t know.

In medical science, a logical theory and a viable treatment option are not even close. Case reports and theories are NOT adequate scientific studies.  They can be wrong, twisted, manipulated, made-up, self-serving reports used to promote untested treatments by appealing to the parents’ hopes, preying on desperation, and promising to empower them to help their children. Sadly, this is how I would characterize many alternative biomedical treatments for autism at this time. – Ilene

Autism: Kids put at risk

By Trine Tsouderos and Patricia Callahan, LA Times
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Phil's Favorites

An economist talks turkey: 5 facts about Thanksgiving pricing

 

An economist talks turkey: 5 facts about Thanksgiving pricing

Courtesy of Jay L. Zagorsky, Boston University

Few foods are tied as closely to one holiday as turkey is to Thanksgiving. At almost every Thanksgiving feast an enormous turkey is one of the central attractions.

In fact, the typical whole turkey sold in the U.S. weighs about 15 pounds, is 70 percent white meat and has more protein than chicken or beef. But the more important question is how much will it cost?

So before shelling out your hard-earned money for a large bird, there are five fast financial facts I think you should know.

Your’re getting ...

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Kimble Charting Solutions

King Dollar Creating A Topping Pattern This Week?

Courtesy of Chris Kimble.

CLICK ON CHART TO ENLARGE

King Dollar has spent the majority of the past 7-years inside of rising channel (1), as it’s created a series of higher lows and higher highs.

The 2018 rally has it kissing the underside of potential resistance this week at (2), where it could be creating a bearish reversal pattern. This one week action has NOT changed the upward trend in King Dollar.

If it breaks rising support at (3), odds favor that some selling pressure takes place in the US$, which metals would lov...



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Zero Hedge

IMF Sounds The Alarm On Leveraged Lending

Courtesy of ZeroHedge. View original post here.

Five months after the IMF sounded the alarm over junk bonds, it has now moved on to the credit market bogeyman du jour and overnight joined others such as the Fed, BIS, Oaktree, JPMorgan, and Guggenheim in "sounding the alarm on leveraged loans."

By Tobias Adrian, ...



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Insider Scoop

A Peek Into The Markets: US Stock Futures Fall, Dow Futures Down 100 Points

Courtesy of Benzinga.

Related SPY A Peek Into The Markets: US Stock Futures Up Ahead Of Economic Reports A Peek Into The Markets: US Stock Futures Edge L...

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Members' Corner

NY Times: OPERATION INFEKTION

 

This is a three-part Opinion Video Series from NY Times about Russia’s meddling in the United States’ elections as part of its "decades-long campaign to tear the West apart." This is not fake news. Read more about the series here.

OPERATION INFEKTION

RUSSIAN DISINFORMATION: FROM COLD WAR TO KANYE

By Adam B. Ellick and Adam Westbrook

EPISODE 1

MEE...



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Chart School

Weekly Market Recap Nov 11, 2018

Courtesy of Blain.

This past week was saw another positive move up by bulls – especially in the Dow and S&P 500; the NASDAQ was not quite as enthusiastic.   Wednesday’s rally was on the legs of an election that was seen as market friendly or at least not as bad as it could have been.   Essentially – paying people a lot of money to get nothing done the next 2 years – woo hoo!

The market is interpreting Wedneday’s result as insuring that “no big things will get done,” in Washington between now and 2020, Craig Birk, chief investment officer at Personal Capital told MarketWatch. “The market appreciates the relative certainty of the slow legislative agenda.” he said.

“As President Trump plans his 2020 reelection campaign, a gridlocked Congress is unlik...



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Digital Currencies

Bitcoin's high energy consumption is a concern - but it may be a price worth paying

 

Bitcoin's high energy consumption is a concern – but it may be a price worth paying

Shutterstock

Courtesy of Steven Huckle, University of Sussex

Bitcoin recently turned ten years old. In that time, it has proved revolutionary because it ignores the need for modern money’s institutions to verify payments. Instead, Bitcoin relies on cryptographic techniques to prove identity and authenticity.

However, the price to pay for all of this innovation is a high carbon footprint, created by Bitc...



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ValueWalk

Vilas Fund Up 55% In Q3; 3Q18 Letter: A Bull Market In Bearish Forecasts

By Jacob Wolinsky. Originally published at ValueWalk.

The Vilas Fund, LP letter for the third quarter ended September 30, 2018; titled, “A Bull Market in Bearish Forecasts.”

Ever since the financial crisis, there has been a huge fascination with predictions of the next “big crash” right around the next corner. Whether it is Greece, Italy, Chinese debt, the “overvalued” stock market, the Shiller Ratio, Puerto Rico, underfunded pensions in Illinois and New Jersey, the Fed (both for QE a few years ago and now for removing QE), rising interest rates, Federal budget deficits, peaking profit margins, etc...



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Biotech

Gene-editing technique CRISPR identifies dangerous breast cancer mutations

Reminder: Pharmboy is available to chat with Members, comments are found below each post.

 

Gene-editing technique CRISPR identifies dangerous breast cancer mutations

Breast cancer type 1 (BRCA1) is a human tumor suppressor gene, found in all humans. Its protein, also called by the synonym BRCA1, is responsible for repairing DNA. ibreakstock/Shutterstock.com

By Jay Shendure, University of Washington; Greg Findlay, ...



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Mapping The Market

Mistakes were Made. (And, Yes, by Me.)

Via Jean-Luc:

Famed investor reflecting on his mistakes:

Mistakes were Made. (And, Yes, by Me.)

One that stands out for me:

Instead of focusing on how value factors in general did in identifying attractive stocks, I rushed to proclaim price-to-sales the winner. That was, until it wasn’t. I guess there’s a reason for the proclamation “The king is dead, long live the king” when a monarchy changes hands. As we continued to update the book, price-to-sales was no longer the “best” single value factor, replaced by others, depending upon the time frames examined. I had also become a lot more sophisticated in my analysis—thanks to criticism of my earlier work—and realized that everything, including factors, moves in and out of favor, depending upon the market environment. I also realized...



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OpTrader

Swing trading portfolio - week of September 11th, 2017

Reminder: OpTrader is available to chat with Members, comments are found below each post.

 

This post is for all our live virtual trade ideas and daily comments. Please click on "comments" below to follow our live discussion. All of our current  trades are listed in the spreadsheet below, with entry price (1/2 in and All in), and exit prices (1/3 out, 2/3 out, and All out).

We also indicate our stop, which is most of the time the "5 day moving average". All trades, unless indicated, are front-month ATM options. 

Please feel free to participate in the discussion and ask any questions you might have about this virtual portfolio, by clicking on the "comments" link right below.

To learn more about the swing trading virtual portfolio (strategy, performance, FAQ, etc.), please click here ...



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Promotions

Free eBook - "My Top Strategies for 2017"

 

 

Here's a free ebook for you to check out! 

Phil has a chapter in a newly-released eBook that we think you’ll enjoy.

In My Top Strategies for 2017, Phil's chapter is Secret Santa’s Inflation Hedges for 2017.

This chapter isn’t about risk or leverage. Phil present a few smart, practical ideas you can use as a hedge against inflation as well as hedging strategies designed to assist you in staying ahead of the markets.

Some other great content in this free eBook includes:

 

·       How 2017 Will Affect Oil, the US Dollar and the European Union

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All About Trends

Mid-Day Update

Reminder: Harlan is available to chat with Members, comments are found below each post.

Click here for the full report.




To learn more, sign up for David's free newsletter and receive the free report from All About Trends - "How To Outperform 90% Of Wall Street With Just $500 A Week." Tell David PSW sent you. - Ilene...

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About Phil:

Philip R. Davis is a founder Phil's Stock World, a stock and options trading site that teaches the art of options trading to newcomers and devises advanced strategies for expert traders...

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